>>76404167Yes, estrogen does influence testosterone levels in men, primarily through negative feedback on the hypothalamic-pituitary-gonadal (HPG) axis.
Here’s how it works:
---
The HPG Axis (Hormonal Control System)
1. Hypothalamus releases GnRH (gonadotropin-releasing hormone)
2. GnRH stimulates the pituitary gland to release:
LH (luteinizing hormone) stimulates testosterone production in the testes
FSH (follicle-stimulating hormone) supports sperm production
3. Testosterone (and some of it converted into estradiol, a form of estrogen) then:
Feeds back to the hypothalamus and pituitary
Inhibits further release of GnRH, LH, and FSH
---
Estrogen's Role
In men, estrogen is mostly made from testosterone via the enzyme aromatase
Once produced, estrogen acts as a brake on the HPG axis, just like testosterone
This reduces LH and FSH, which in turn lowers testosterone production
---
Clinical Example: Too Much Estrogen
High estrogen levels (from obesity, liver issues, or aromatase overactivity) can:
Suppress LH and FSH
Decrease natural testosterone production
Cause symptoms like low libido, fatigue, gynecomastia (man boobs), infertility
---
Bottom Line:
> Yes, estrogen influences testosterone in men — mainly by suppressing testosterone production through hormonal feedback mechanisms.Let me know if you want to explore what affects aromatase activity or how estrogen blockers work in TRT or bodybuilding.