Most estradiol vials are garbage - /lgbt/ (#40584511) [Archived: 313 hours ago]

Anonymous
8/2/2025, 8:48:47 PM No.40584511
horse-urine-c-3600636116
horse-urine-c-3600636116
md5: bd173776f0f13a26826a2950c648f5bb🔍
Not naming any sources because don't want to hear "Buy an ad" or slander individuals

I'm sick and tired of seeing the piss poor standards in homebrew estradiol. Having a lot of knowledge (autistic hyperfixation) of the back end of both anabolics and the current and historical HRT market), the low standards and quality are honestly a garbage thing to see. This is especially in recent times.

Things i've personally seen

1: Hairs, dust, or rust in vials

2: Crappy formulations with 40%+ Benzyl Benzoate, which are never needed and are basically just thinning out and having you inject a scabies medicine. Also causes reactions in the vast majority of people. This is why a lot of people say to inject IM, it's because the irritation is less noticeable when it's injected deeper.

3: Shitty amazon/GMC carrier oils. Crap excipients

4: No Benzyl alcohol vials (absolutely unacceptable in a multi use vial)

5: No third party testing

6: Underage anime porn boxes with instructions to keep away from parents. Basically advertising directly to U18's, terrible optics.

Given the price comparison to the anabolics market, it's frustrating to see how little pride many vendors take in making their product. I've seen MA projects that give stuff away that have higher standards for what they do.

Not all anabolic vendors are great, in fact a lot are worse than estradiol vendors, but their best vendors are better than DIYHRT suppliers by a long shot. The FtM's take a W here.

If you're gonna charge for a vial, have some standards and buy proper lab equipment, put some effort into what you do. Lives are at stake.
Replies: >>40585355 >>40585370 >>40585438 >>40585462 >>40585988 >>40586100 >>40586203 >>40586214 >>40587079 >>40587675 >>40587677 >>40587699 >>40587761 >>40587792 >>40590037 >>40591011 >>40592101 >>40592179
Anonymous
8/2/2025, 10:20:59 PM No.40585355
>>40584511 (OP)
Make a guide or build your own business.
Replies: >>40585988
Anonymous
8/2/2025, 10:21:44 PM No.40585370
>>40584511 (OP)
youre talking like otoko is the only source
Anonymous
8/2/2025, 10:28:00 PM No.40585438
>>40584511 (OP)
>6: Underage anime porn boxes with instructions to keep away from parents. Basically advertising directly to U18's, terrible optics.

Surely not!
Replies: >>40586258
Anonymous
8/2/2025, 10:30:12 PM No.40585462
>>40584511 (OP)
DIY is 99% just a larp which is why a lot of DIY youngshits have shit and sometimes non existent results. Doctor will prescribe you sugar pills for less.
Replies: >>40586322
Anonymous
8/2/2025, 10:41:10 PM No.40585581
Lena has never done me wrong
Anonymous
8/2/2025, 11:19:54 PM No.40585988
Screenshot 2025-08-02 at 5.15.01 PM
Screenshot 2025-08-02 at 5.15.01 PM
md5: 0d6e78a0c3e0496c01f089fc8aee59b9🔍
>>40584511 (OP)
>Crappy formulations with 40%+ Benzyl Benzoate
In fairness to homebrewers, they are more or less just copying pharma company recipes.
It's fine for most people, and those who don't have good luck with it can simply buy from Voix Celeste or OpenGateLabs.
>>40585355
This info is out there. Roiders and trannies alike have been publishing info on how to do this properly for decades.
Anonymous
8/2/2025, 11:34:02 PM No.40586100
>>40584511 (OP)
the one i got had somewhere like a 20-30% concetration of benzyl benzoate and also had benzyl alcohol
overall i have not had any reactions so far aside from sometimes slight muscle soreness the next day if i fuck up the injection,
my levels were also exactly as predicted going off the testing for concentration (it was somewhere around like 39.5mg/ml
no particulate matter, rust, or hair in mine either
overall im happy with my diy enough that i use it over the legit estradiol cypionate im prescribed because it's just easier to inject 0.15ml vs 0.75ml
the rubber stopper is also good quality, much better than legit ones which were so bad that a piece fell into my medication one time even though it's punctured much less over it's lifetime, the little container for it was also good and easy to use
Anonymous
8/2/2025, 11:47:28 PM No.40586203
>>40584511 (OP)
interesting complaints
personally after doing diy for a few years I have never seen hair or other contaminants in the vials
I haven't been paying attention to benzyl benzoate concentration, but at most I would get very mild allergic reactions to otokonoko sometimes
the carrier oils are pretty much always better than you get from pharma because they use thinner oils that are easier to inject
third party testing is common
and anime on the boxes is exclusive to otokonoko. It kinda seems like you just don't like otokonoko and are generalizing the entire industry. Anyway you're acting like a credit card company about some harmless hentai, personally I do have one of those boxes as a collector's item and a piece of memorabilia.
stop concern trolling
Anonymous
8/2/2025, 11:49:14 PM No.40586214
>>40584511 (OP)
You bought from fucking Femboy Pharma... what on earth did you expect from being endorsed by keffals and lolicow vaush? Literally every other homebrewer, to a rounding error, does it better than them.

FWIW I went with Lena and the vial looked pristine, no evidence of contamination to my eyes. Unlike some homebrewers she has the decency to leave the metal cap on the rubber stopper cover. 50mg/ml isn't for everyone though, although it's been fine for me.

Also, might as well, short needle rant time:
For DIY, all you ever need are fixed 1ml insulin needles. You waste less that way. There's a hilarous graph on that keffals site that says that such needles are "very rare outside of medical institutions" which is crazy because I know of fucking druggies using this shit for fucks sake
Replies: >>40586912
Anonymous
8/2/2025, 11:54:24 PM No.40586258
>>40585438
Thats one vendor doing that, not multiple
Anonymous
8/3/2025, 12:01:58 AM No.40586322
>>40585462
KEK
i got d cups off DIY
kys.
Replies: >>40589779
Anonymous
8/3/2025, 1:03:15 AM No.40586912
>>40586214
>You waste less that way
why not just do the method where you turn the syringe upside down, draw up a bit of air, then flick the syringe till it all goes to the top (so the only thing you waste is the air
so far it has worked very well for me
Replies: >>40587642
Anonymous
8/3/2025, 1:27:50 AM No.40587079
>>40584511 (OP)
I make my own for myself and they're fine. No visible contam. I don't add benzyl benzoate, 10mg/ml concentration, and use chlorobutanol instead of benzyl alcohol (slightly altered Pfizer formula)
I use a still air box and depyrogenize my vials and equipment beforehand. Vials also get a dry sterilization after crimping.
I have yet to suffer any negative effects and my levels are spot on
Replies: >>40587310
Anonymous
8/3/2025, 1:59:13 AM No.40587310
>>40587079
What equipment do you use for depyrogenization and sterilization?
Replies: >>40589731
Anonymous
8/3/2025, 2:45:34 AM No.40587642
>>40586912
how much are you spending on needles etc?britbong but i pay under 20 quid for 100 injections
Replies: >>40587731
Anonymous
8/3/2025, 2:49:41 AM No.40587675
>>40584511 (OP)
ive been using *pen *ate labs hrt hopefully its not sugar oil
Anonymous
8/3/2025, 2:50:09 AM No.40587677
>>40584511 (OP)
>5: No third party testing
there literally is a site that does third party testing and it has confirmed that all the major suppliers are good
shut the fuck up with this retarded fear mongering thread and DIE.
Anonymous
8/3/2025, 2:54:05 AM No.40587699
>>40584511 (OP)
for once im thankful to be a buck broken insurance tranny
Anonymous
8/3/2025, 2:58:05 AM No.40587731
>>40587642
i just use the ones from my pharmacy since i have a legit prescription
Replies: >>40587821
Anonymous
8/3/2025, 3:03:25 AM No.40587761
>>40584511 (OP)
WHY don't you simply take EV in tablet form?
Replies: >>40589747
Anonymous
8/3/2025, 3:08:48 AM No.40587792
>>40584511 (OP)
honestly sometimes i wonder if the "hrt doesn't do anything" posters just are buying from a shitty supplier who's scamming them or something
Replies: >>40589779 >>40590037
Anonymous
8/3/2025, 3:14:20 AM No.40587821
>>40587731
probably getting hondosed icl
Replies: >>40589996
Anonymous
8/3/2025, 6:59:12 AM No.40589731
>>40587310
Toaster oven that goes up to 280C for depyro and a pressure cooker for sterilization. I use indicator tape to make sure I reached proper temp
Replies: >>40589835
Anonymous
8/3/2025, 7:00:25 AM No.40589747
>>40587761
EV is trash and doesn't last as long
Anonymous
8/3/2025, 7:03:32 AM No.40589779
>>40587792


>>40586322
care to talk a little about it? I'm about to start hrt likely through diy bc waitlists are over a year here and was wondering which method (pills injections etc), doses, stack, etc? any little tricks you do that seem to work well for you?
Anonymous
8/3/2025, 7:10:20 AM No.40589835
>>40589731
Damn, same equipment I use.
I guess using kitchen appliances for this stuff is pretty meta.
Replies: >>40590055
Anonymous
8/3/2025, 7:30:42 AM No.40589996
>>40587821
im diy
Anonymous
8/3/2025, 7:37:53 AM No.40590037
>>40587792
>>40584511 (OP)
when you say bad quality diy, is the estradiol content itself ruined or are you referring to the estradiol content being much more diluted than they say?
Replies: >>40590254
Anonymous
8/3/2025, 7:38:23 AM No.40590038
what do i need to make my own E
Replies: >>40590104 >>40591769
Anonymous
8/3/2025, 7:41:27 AM No.40590055
>>40589835
For small batches it works great. They get up to temp just fine. Every tranner can make enough HRT for herself and her friends with some patience and following proper sterile technique
Anonymous
8/3/2025, 7:49:00 AM No.40590104
>>40590038
https://www.dropbox.com/s/nujaw6e1lb19twr/HRT%20Homebrew.pdf
And
https://www.dropbox.com/scl/fi/248gg9csugb6uhuft1qkk/Michael-J-Akers-Sterile-drug-products.pdf?rlkey=3iwicrc8eqpc1i7wdvwqjsk3z&e=1&st=q2ijwupa&dl=0
Replies: >>40590126 >>40590133 >>40590491
Anonymous
8/3/2025, 7:52:53 AM No.40590126
>>40590104
could you upload them to catbox or litterbox
Replies: >>40590471
Anonymous
8/3/2025, 7:54:31 AM No.40590133
>>40590104
God bless you, i got estrogen undecylate and im gonna make it as soon as i buy a pressure cooker
Replies: >>40590471
Anonymous
8/3/2025, 8:18:51 AM No.40590254
>>40590037
usually its the sterilization process thats sketchy

transharmreduction dot org
Anonymous
8/3/2025, 9:03:32 AM No.40590471
>>40590126
I set it up so you can download without the app. I jumped through enough hoops, making burner accounts, etc to make it available. I don't wanna jump through any more.
Feel free to download and reupload it to the site of your choosing and share the link
>>40590133
Check out fb marketplace (make a burner account if you dont have one), letgo/offerup, thrift store, etc. there's always some older lady getting rid of her old one. My first one was a 6qt and it worked great for all my tools and vials
Replies: >>40590666
Anonymous
8/3/2025, 9:08:12 AM No.40590491
>>40590104
you can buy a few hundred miligrams of stuff from ali? i thought it had to be a whole shipping container at least
Replies: >>40590534
Anonymous
8/3/2025, 9:14:45 AM No.40590534
>>40590491
I'd go with made-in-china. Some vendors will bitch and want you to order a kg but thats waaaay too much unless you're making enough for a large community. Just order like 10-20 grams for a couple hundred bucks depending on the seller. I got 10 the first time and 20 the second. 10gs is enough for 38 years if you keep it out of light and away from moisture (5mg/wk)
Anonymous
8/3/2025, 9:46:24 AM No.40590666
meanwhile
meanwhile
md5: bc2341aee7598f3df08defae05746121🔍
>>40590471
>I set it up so you can download without the app
you set it up wrong
>I jumped through enough hoops, making burner accounts, etc to make it available. I don't wanna jump through any more.
the interface of catbox is select the pdf on your computer and then upload it
Replies: >>40590994
Anonymous
8/3/2025, 10:43:37 AM No.40590994
>>40590666
Try opening in desktop mode then. It's working fine on my device not signed in. Learn to troubleshoot and figure it out
You want me to mix your vials too?
Replies: >>40591014
Anonymous
8/3/2025, 10:46:34 AM No.40591011
>>40584511 (OP)
>Underage anime porn boxes with instructions to keep away from parents. Basically advertising directly to U18's, terrible optics.
i agreed with you until this point. the otokonoko iconography must stay.
Anonymous
8/3/2025, 10:47:21 AM No.40591014
>>40590994
>Try opening in desktop mode then
I am on a desktop and using firefox
>Learn to troubleshoot and figure it out
my troubleshooting involved asking you to use the free and commonly used file host catbox
Replies: >>40591071
Anonymous
8/3/2025, 10:56:08 AM No.40591071
>>40591014
okay I figured it out and now I will put the two files on literbox and they will expire in three days
https://litter.catbox.moe/wtcct5wtgp228ncu.pdf
https://litter.catbox.moe/6n6j0lpzstfql5x0.pdf
Anonymous
8/3/2025, 1:15:34 PM No.40591769
>>40590038
Ovaries.

But in all seriousness, if you're just starting out, make some E gel first to get a feel for it. The risk of fucking up E gel is much lower, and almost non-existant when used. Injections have to be done right from start to finish or else you could kill yourself from sepsis.
Anonymous
8/3/2025, 1:27:56 PM No.40591856
it's already estrogen when you order it raw so wtf are you making
Anonymous
8/3/2025, 1:35:48 PM No.40591903
What lab equipment do homebrewers need
Anonymous
8/3/2025, 2:19:11 PM No.40592101
>>40584511 (OP)
thank you for a dogshit, substanceless critique.

t. ranny who broadly agrees with you
Anonymous
8/3/2025, 2:31:42 PM No.40592179
1751837293576154
1751837293576154
md5: 054de89e226cd1e33edb6598fd32187d🔍
>>40584511 (OP)
heres the actual critique btw OP:

- otokonoko do not filter their vials, or do so poorly. we have evidence in homebrew circles of microparticles in the vials implying this. theyre not the only vendor with a reputation for poor or absent filtration efforts.
- most vial formulations are bad, failing to balance convenience with reactions. no matter who you buy a vial from someone somewhere will be getting lumps from it, and we only have so many vendors.
- prices are way higher than high quality roid vendors per vial. those who arent expensive have other downsides.

there is at least one roid vendor selling injectable estradiol, but the concentration is comically low (10mg/ml). i really hope this changes, the homebrew community needs a serious shakeup.

the box art means literally fucking nothing, i couldnt give a fuck if theres straight up gay sex on the vial box so long as the vial itself is good.

also im pretty sure lillians tablet production technique is terrible. not beyond whats common with cheap anabolics, but still not ideal and not comparable with pharma stuff.
Replies: >>40593936
Anonymous
8/3/2025, 2:39:47 PM No.40592237
I’m detrooning because I did otoko for a few years and wasn’t happy with the results
Anonymous
8/3/2025, 6:50:52 PM No.40593936
>>40592179
>comically low
There's good reasons for this. Pfizer does 5mg/ml.
No reason to add benzyl benzoate to increase solubility, one less chemical to risk irritation
Lower concentration means you won't use the vial as long, reducing the risk of compromising the integrity of the rubber seal. Less holes and holes wont get large enough to let in contam
I make mine this concentration for this reason