Anonymous
ID: 4h9ysZgz
6/22/2025, 12:09:58 PM No.508312856
https://www.courant.com/2025/06/21/people-with-severe-diabetes-are-cured-in-small-trial-of-new-drug/
"A single vaccine may have cured 10 out of 12 people with the most severe form of Type 1 diabetes," the news said.
"One year later, these 10 patients no longer need insulin. The other two patients need much lower doses than previously."
Is it permanent change? We dont know but 12 months already is indicating towards that direction.
Patients in the study began to need less and less insulin within a few months of being infused with new islet cells which were modified by mRNA and most stopped needing treatment altogether at about six months.
If the study continues to show positive results, the company expects to submit an application to the FDA next year. "For the short term, this looks promising" for severely affected patients like those in the study," said Dr. Irl B. Hirsch, a diabetes expert at the University of Washington who was not involved in the study.
But patients in the trial had to stay on drugs to prevent the immune system from destroying the new cells. Suppressing the immune system, he said, increases the risk of infections and, over the long term, can increase the risk of cancer... Patients may have to take the immunosuppressant drugs for the rest of their lives, the Vertex spokesperson said.
"A single vaccine may have cured 10 out of 12 people with the most severe form of Type 1 diabetes," the news said.
"One year later, these 10 patients no longer need insulin. The other two patients need much lower doses than previously."
Is it permanent change? We dont know but 12 months already is indicating towards that direction.
Patients in the study began to need less and less insulin within a few months of being infused with new islet cells which were modified by mRNA and most stopped needing treatment altogether at about six months.
If the study continues to show positive results, the company expects to submit an application to the FDA next year. "For the short term, this looks promising" for severely affected patients like those in the study," said Dr. Irl B. Hirsch, a diabetes expert at the University of Washington who was not involved in the study.
But patients in the trial had to stay on drugs to prevent the immune system from destroying the new cells. Suppressing the immune system, he said, increases the risk of infections and, over the long term, can increase the risk of cancer... Patients may have to take the immunosuppressant drugs for the rest of their lives, the Vertex spokesperson said.
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