>>508539810not necessarily addiction, but definitely drug abuse.
marijuana/amphetamines/psychostimulants
look up hypersexuality with those
long-term we already know marijuana has a good chance to turn you schizophrenic. long-term effects of prescription amphetamines isn't well known but i'll bet in 30 years we'll see it turns adhd autists into trannies via some longtitudinal study
street meth definitely has stronger effects, maladaptive sexual behaviour
https://www.nature.com/articles/npp20171
if there are underlying mental illnesses it's exacerbated
if there are none, then they'll get some eventually