Anonymous
(ID: b/fFh4JB)
6/25/2025, 10:08:02 PM
No.508720537
6/25/2025, 10:08:02 PM
No.508720537
>>508720427
>Impaired DNA Repair Mechanisms:
Concern: Some claim mRNA vaccines, particularly via spike protein, might interfere with DNA repair pathways (e.g., BRCA1 or p53), increasing cancer risk.
Evidence: A 2021 study suggesting spike protein affects DNA repair (Jiang & Mei, Viruses) was conducted in vitro and has been criticized for methodological flaws and lack of real-world relevance. No clinical evidence supports impaired DNA repair in vaccinated individuals, and population studies show no increased cancer rates.
>Chronic Inflammation:
Concern: Persistent inflammation from mRNA vaccines could create a pro-tumorigenic environment.
Evidence: mRNA vaccines cause transient inflammation as part of the immune response, resolving within days. No studies link this to chronic inflammation. Real-world data from millions of vaccinated individuals show no increase in cancer-related inflammatory conditions.
>Dysregulation of the Immune System:
Concern: Vaccines might overstimulate or suppress immunity, allowing cancer cells to proliferate.
Evidence: mRNA vaccines temporarily activate innate and adaptive immunity without causing long-term dysregulation. Large-scale studies (e.g., VAERS, EudraVigilance) show no patterns of immune-related diseases or cancer linked to vaccines. Temporary lymph node swelling is a known, benign side effect.
>Activation of Oncogenic Pathways:
Concern: Vaccine components could trigger pathways (e.g., MAPK, PI3K) that promote cancer.
Evidence: No mechanistic studies or clinical data demonstrate mRNA vaccines activate oncogenic pathways. The spike protein is expressed briefly and cleared, with no evidence of interaction with cancer-related pathways. Regulatory assessments confirm no oncogenic potential.
>Impaired DNA Repair Mechanisms:
Concern: Some claim mRNA vaccines, particularly via spike protein, might interfere with DNA repair pathways (e.g., BRCA1 or p53), increasing cancer risk.
Evidence: A 2021 study suggesting spike protein affects DNA repair (Jiang & Mei, Viruses) was conducted in vitro and has been criticized for methodological flaws and lack of real-world relevance. No clinical evidence supports impaired DNA repair in vaccinated individuals, and population studies show no increased cancer rates.
>Chronic Inflammation:
Concern: Persistent inflammation from mRNA vaccines could create a pro-tumorigenic environment.
Evidence: mRNA vaccines cause transient inflammation as part of the immune response, resolving within days. No studies link this to chronic inflammation. Real-world data from millions of vaccinated individuals show no increase in cancer-related inflammatory conditions.
>Dysregulation of the Immune System:
Concern: Vaccines might overstimulate or suppress immunity, allowing cancer cells to proliferate.
Evidence: mRNA vaccines temporarily activate innate and adaptive immunity without causing long-term dysregulation. Large-scale studies (e.g., VAERS, EudraVigilance) show no patterns of immune-related diseases or cancer linked to vaccines. Temporary lymph node swelling is a known, benign side effect.
>Activation of Oncogenic Pathways:
Concern: Vaccine components could trigger pathways (e.g., MAPK, PI3K) that promote cancer.
Evidence: No mechanistic studies or clinical data demonstrate mRNA vaccines activate oncogenic pathways. The spike protein is expressed briefly and cleared, with no evidence of interaction with cancer-related pathways. Regulatory assessments confirm no oncogenic potential.