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>Tumor Microenvironment Alteration:
Concern: mRNA vaccines might alter the tumor microenvironment, promoting cancer growth.

Evidence: No studies show mRNA vaccines affect tumor microenvironments. In contrast, mRNA-based cancer vaccines are designed to modify tumor microenvironments to enhance anti-tumor immunity, suggesting a protective rather than harmful effect.

>Alteration of Immune Surveillance:
Concern: Vaccines could impair the immune system’s ability to detect and eliminate precancerous cells.

Evidence: mRNA vaccines enhance immune surveillance by stimulating T-cell and antibody responses. No population-based studies (e.g., cancer registries) indicate reduced immune surveillance or increased cancer incidence post-vaccination.