>>12412933 (OP) (dubs)
In summary, intermittent fasting has shown positive effects on weight loss, in addition to reducing insulin resistance and favorably shifting the levels of leptin and adiponectin. Pre-clinical and clinical studies have demonstrated that intermittent fasting has a wide range of benefits for many diseases, including obesity, T2DM, and hypertension, and in improving cardiovascular risk factors. One argument against intermittent fasting is that, despite extensive animal data, many clinical trials have failed to show as significant improvements of intermittent fasting over caloric restriction. In the absence of large randomized controlled trials testing the efficacy and side effects of intermittent fasting in individuals with MetS, prediabetes and T2DM for extended durations, it is difficult to ascertain the risk to benefit ratio of the different intermittent fasting regimens. Studies assessing long-term follow-up are needed for assessing efficacy as a permanent life style approach.
Your fortune: Bad Luck
