Well researched games or good-games-despite-iffy research with Mesoamerican content:

>Aztez: curayzee 2d action game with pseudo rougelike/lite aspects and strategy gameplay in the overworld, well researched but very stylized aztec theme
>Tlatoani: Aztec cities: Very well researched impressions games style isometric citybuilder, Early Access
>Expeditions Conquistador: tactical RPG with visual novel/choose your own adventure style branching narrative. authenticity is kinda eh but it's a good game
>Sixth Sun (saveslothstudio): Metroidvania with a Mesoamerican codex themed art style. Upcoming, looks very cool
>Plus Ultra Legado: Metroidvania where you play as a Conquistador, seems moderately well researched, Upcoming.
>Ancient Tale: ixkik' (Roddanchill), 3d action/adventure game with a Maya theme, looks pretty promising, Upcoming
>Pawarumi: neon-punk mesoamerican futurist spaceship shoot em up game. Seems very loose in terms of cultural influences but neat
>Kotal Kahn in MKX and MK11: Actually a pretty solid adaptation of the Aztec war god Huitzilopochtli, if given slack since MK is all about 80s style tropes
>Marlow Briggs and the Mask of Death: nonsense n terms of the historical stuff but it is a weirdly competent God of War clone you can buy for like 99 cents
>Flower Wars (Roblox, by flowerwars1438): I don't know shit about Roblox but seems good
>Mesoamerica Universalis: Abandoned EU4 overhaul, was being worked on by archeologists
>The Medieval 2 Total War mod "Rise of the Quetzal" and the Age of Mythology "The Return of the Gods" mod: Seems decent, haven't given them a close look
>Pokemon Sage: Fangame made by /vp/ with a latin american theme. Questionable Mesoamerican cultural elements but very high quality, has a demo but isn't finished
>Tlalocmon (Digimon): VERY well researched with subtle iconography, even if visually it doesn't look it at a glance

t. Mesoanon

Also not vidya but read/buy Codex Black and the upcoming Aztec Batman film so we get more of both