>>149742901
Matt and Trey made a show about Bush but it was less about outright ridiculing him and more about making fun of sitcom tropes. They explicitly stated that they wanted him to be a likeable character
Obama? They had him featured in the season 12 election episode and some more throughout his terms. He's presented from neutral to cool, then again, so was McCain in that episode. They made Obama's supporters look like retard though. Some jokes have also been said about Obama not changing anything.
Biden was honestly a missed opportunity, they should have featured him at least once.
Hilary Clinton has been made fun of quite a bit (The Snuke)