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6/30/2025, 11:49:58 AM
>A study published in GeroScience (2023) by the Interventions Testing Program (ITP), supported by the National Institute on Aging, found that AX3 Bio-Pure Astaxanthin extended the median lifespan of male UM-HET3 mice by 12% (p = 0.003, log-rank test) when administered at 1840 ppm starting at 12 months of age. The study highlighted astaxanthin's role as an Nrf2 activator, reducing oxidative stress and inflammation, which are key factors in aging. However, no significant lifespan extension was observed in female mice, suggesting potential sex-specific effects. The authors noted astaxanthin's favorable localization in mitochondria and its excellent safety profile as reasons for its promise as a longevity candidate.
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