Charon can set up an uninteractable Medusa storm, but it requires 2 turns of prep (Laura on 3 and Charon on 5) and 2 super evo points, so you better make damn sure they're at 10 health by turn 7.
So you effectively have 4 turns to do 10 damage to their face by any means necessary..the current card pool doesn't terribly facilitate this, but I'm hopeful the rest of the reveals will help.