I ran a semi-hexcrawl once to try it, as in it was a proper campaign with an overarching plot and side quests but when the party wasn't pressed for time, they could fuck around and explore on their own, and even when pressed for time they had to blindly traverse uncharted areas.
It was fairly fun, being able to exactly calculate how long travelling takes satisfied my autism. I'm not sure if I will use the method again though, in my current game I went the opposite way and now there's no map whatsoever, locations and travel time are handwaved, the focus is entirely on destinations with 0 focus on travel.