How do you leave your house in isekai without prebuffing?
>effortless armor, freedom of movement and haste for maximum movement speed
>death ward to prevent level drain
>protection from evil to prevent mind control
>aid, guidance, bless, enchant stats, shield of faith, shield, unbreakable heart, heroism
>protection from petrification
>delay poison
>stoneskin, barkskin, blur, mirror image
>echolocation, true seeing
>protection from energy, spell resistance, resist energy
And it's only to prevent debuffs. Prebuffing is not going to protect you against skill checks, because persuasion, intimidation and bluff work like brainwashing.