>>538167854
Since the last time I played they've added a special mode where you can get a large variety of effects that are typically upside + downside, though the severity of the upside and downside tend to vary. That middle one means my guys are going to age one year every single in game day which might make play completely impossible, but I took it as I'm intensely curious how much exactly it reduces medicine tolerance by. Depending on how much by and how difficult it's going to be for me to urgently grab some life and morrow pills or something, this is either going to be insanely OP or completely unworkable.
Either way I might restart as I didn't get offered the main modifier I heard about which was the main reason I got the urge to return to the game, but for now it's good to experiment and figure out how to play again.