Is is worth it to fly first class to these destinations for relaxation, culture, and adventure?

Starting point Europe
(Country irrelevant because first class flights are not in every country)

Argentina + Chile
>Although if going so far might as well see more countries in south america

Australia + New Zealand + Antarctica
>also makes sense to see Oceania, possibly flying to SE Asia for a trip and then going from there

Japan
>Hokkaido or Okinawa depending on the season, but can make stops in Asia on the way

I have the funds easily for two people and could do a trip each year, but I'm not a fan of long distance flying so it's better if the trip is a one time thing or has shorter stops than a long haul

Is it worth it flying first class?