What about some kind of viral infection experiment?

Like, a small range of posters throughout the site are designated Patient Zero and the virus spreads randomly to other posters in whatever threads they post in.

The game becomes trying to survive the entire day without getting infected. Maybe include a scoreboard at the top of the page showing the number of active posts on 4chan, broken up by how many are infected and how many are safe. Maybe if a certain % of posters in a thread are infected the theme changes to a creepy infected-colored one, to add to the immersion.

i dont know how the mechanics of this would work but experiments are fun