2nd game was picked because they're attempting to work around V3's ending by retroactively establishing its content as the product of a programmatic error rooted in an issue gone wrong from 2's cyberized, virtual, dreamscape setting.
In other words, they're trying to say V3 was itself isolated from every other Danganronpa rather than a part of its continuum and was itself purely fictional, but its characters attained enough sentience to try and break past their programmatic mold.
Naturally, they'll direct the story thataway to operate in congruence with the whole AI thing. That's the 'in' thing today, after all. Of that, there can be no doubt.
It's also 2x2 because they're merging the content of
1. THH
2. SDR2
3. UDG
4. V3
all into one game. Again, this is possible only because DR2 transpires within a cyberized world.
The characters who'll die and the characters who'll live will all be inverted from its initial content, and the final boss will not be Junko, but will instead be the whole cast of Danganronpa across each game. Those dying and those surviving won't be characters anymore as much the verses through which their life is. Basically, worlds will be fighting. Danganronpa will be pitted against Danganronpa.

With all that said, given that the fanbase (majority) is no longer lunatic men who like tricks, traps, sexy women, romance, confronting wills, kino, debators, and a fight against all, Komatsuzaki Rui's art will be spent in service of drawing worthless CGs of male characters and naturally the scenario will be tainted with shit since Kodaka, under illusion X, mistakenly thinks the cosplayer e-whores give a fuck about his series beyond extracting pointers to attire in order to best milk retards, or that the disabled women incapable of interacting with a story beyond saying 'crazy! it was crazy!' and wanting to read fanfiction of men fucking men are ''people'' worth catering to. Add to that the shit state of the world, and any good you get will be a miracle.