>>723796906
There are enough items in the game to create synergies and powerspikes in my opinion. The greater issue is most of these come available very late in the game and by that point you're already blasting through any encounter without trouble.
I've never really bothered with optimizing the builds because there's not enough challenge in the game. It's just too easy. It's never a question of "what should I do to win this fight", it's "how do I want to win this fight."
Maybe there's a difficulty mod that fixes this issue to a degree, but I doubt it. The enemy healthpools should be at least doubled.