I have some concerns.

1-handed is obviously horrible, but 2-handed forces you into seeker+guardian (or some other combat-focus deck), and you can't play anything outside of that.

The problem is, 3-handed seems far too easy. There are too many little things that compound to help the players. Don't even want to imagine 4.

Recently I've been playing 3-handed on Hard (cruised through Dunwich and Carcosa using only cards released up to those points, using the 2019 taboo list), but I don't see Expert making much of a difference, unless you simply don't play Scrapper/Higher Education/Streetwise.

I think the system is fundamentally flawed, because they have to print campaigns that are beatable with just the cards in it + the core set, but yet they want to give players the illusion that they can keep building fun decks with the whole card pool.