>>151220870
I barely remember any actual good jokes from the segment but it's still one of the most memorable Simpsons segments because people love when cartoon animation does something unexpected.

CGI Homer is well remembered. The highest rated Family Guy episode is the one where they try to imitate Disney animation. A large part of why people like Smiling Friends is because you have no idea what the animation will do so they might randomly do claymation or rotoscoping or even fucking puppetry based on a fairly obscure 1980s British TV show. People LIKE to be surprised.