this is why they age so fast
daily-metabolism magazine:
https://dx.doi.org/10.1016/j.metabol.2025.156259
Take note of the name: ReHMGB1. A new study pinpoints this protein as being able to spread the wear and tear that comes with *time* as it quietly travels through the bloodstream.
This adds significantly to our understanding of aging. The researchers were able to identify ReHMGB1 as a critical messenger passing on the senescence signal by analyzing different types of human cells grown in the lab and conducting a variety of tests on mice.
When ReHMGB1 transmission was blocked in mice with muscle injuries, muscle regeneration happened more quickly, while the animals showed improved physical performance, fewer signs of cellular aging, and reduced systemic inflammation.
