>>715235268 (OP)1. Stop panic dodge rolling. You want to learn how to move around bullets and know what firing pattern enemies use.
2. Learn which enemies are the most dangerous for the room they are in. The poopulons are really bad in big rooms where it takes a while to move between cover. The veteran bullets are bad in small rooms where they can predict your movement
3. Know what guns are good for your passives. Some guns don't work well if you have things like bouncy bullets because they explode away from the enemy. Some guns don't work if they pierce.
4. If you have trouble getting guns, then don't open a chest on the floor until you beat the boss. Bosses auto drop guns if you haven't picked one up on a floor. Guns hold more power for your character then a passive in 80% of cases. Getting something like Ice tray or AK-47 will do more for your run then Heart of Ice or Medikit.