>>2097415
The TEC Supremacy do retain the Novalith cannon, and the Advent Wrath still have the incredibly annoying abiliy to steal your non-capital ships if their Deliverance engine hits the gravity well if your fleet in it (which the AI is very good at targeting quickly). The Advent Reborn can only resurrect their dead ships, which is not really that useful.
The TEC Enclave "only" have the ability to build two starbases (can be really powerful to stop any mere 1000 supply fleet) , and of course their garrison fleets, which overwhelms the enemy in blood, metal and ships.
The Vasari do not have the Kostura cannon anymore, but considering that they have a higher fleet supply than the TEC and Advent and have better ships, they don't need them anyway.
The Vasari Exodus blowing up all planets permanently is going to be extremely annoying for you, as you will lack the planets to build a forward base, and the Vasari Alliance has the toughest ships overall.
One good thing is that the AI is bad at using dark fleets when playing the Vasari. But man, does it love to blow up all the planets it owns far away from its main capital world when being the Exodus.
Anyway, yes, expect superweapons by the fourth hour of gameplay.