>>280258076The premise of the show is based upon the primordial fertility cults that attributed magic and powers to genitalia, which were carried on in Japan throughout all the ages with Shinto.
Yokai are lifeforms that like humans, exist and "live" to a degree, but cannot reproduce and generate life. Some species of aliens, the more advanced ones, suffer from this limitations as well. Therefore human genitalia and the act of reproduction itself become the object of longing for there beings, in their struggle for survival. Even if it's not been explained, and maybe never will, maybe yokai needa quota of human genitalia to stay alive and not fade after a while, and aliens need them to clone themselves and transfer consciousness, needing them pragmatically in addition to philosophically.
Turbo Baba goes after men trying to obtain their testicles also because she's the vengeful spirit of girls being raped and killed basically. Again, sexuality is a central theme, the running man is also a reminder of the importance of that union.
Moreover, the enemies are often beaten by teamwork of the humans, especially male + female, reinforcing the notion of the magic power of the union of the sexes with Okarun being often in black and Momo in white, representing the Yin Yang.
>tl,dr; Dandadan revives the fertility cults of the past in Japan, and Abe would be proud