>>282035622 (OP)
Brotherhood is a series for children where there are only very good guys doing good things and very bad guys who do bad things just because.
On the other hand, FMA 2003 is a seinen in which the faults and mistakes of the past are dragged along and come back and explode in their faces in the form of homunculi, which brings a lot of doubts, suffering and confusion to the protagonists when their mother appears in the form of homunculi, or the son of their teacher reappears as Wrath. Also the development of Lust with her past in Ishbal. And Dante's motivation is somewhat more believable, because the search for immortality is something that alchemists always sought since ancient times. And Ed's father himself has blood on his hands. In Brotherhood, on the other hand, it's all the fault of an evil pokemon and Ed's father is a Gary Stu. Like all the other characters become more flat as for a child audience who just want to see fights with lights and explosions, but without questioning the beliefs of the characters.
While in FMA 2003 Dante questions Ed's beliefs, and the main characters don't have a happy ending with everyone happy, but a more realistic ending where there are losses and negative consequences to their past actions.