>>5001972In the year 1000 AD, Cahokia was more populous than Paris France, and Teotihuacan would have been perhaps the 6th most populous city in the world. The estimates for total native american population in the US, prior to 1600 or so have error bars you could land an airliner on, because a lot of the evidence was destroyed during the resettling of the continent by Europeans, but North America alone was in the neighborhood of 30 million people (some estimate a much higher population), about equivalent to Europe. By 1492, that would have declined to between 15 and 20 million, and by 1776 it had declined to approximately 4 million.
Between 1000 AD and 1750 AD, the amount of tree cover in North America more than doubled as villages were abandoned and horticulture declined, and the advancing of the wilderness was well underway by the time Columbus arrived. Europe as well had experienced significant population swings and the wave of colonization was driven largely by the desire to continue to expand the way that the men of the time's fathers and Grandfathers had in Europe, but the slower pace of communication and trade in the Americas also caused plagues to burn longer than they did in Europe and Asia. There were ~30 million people in Europe in 1000 AD, and that had increased to 76 million or so by 1350, but the succession of plagues in the 1300s and 1400s meant that by 1450, the population of Europe had fallen below the 1000 AD level. It was the recovery and reclamation of abandoned lands in Europe that allowed for the enormous population boom that tripled or quadrupled the population of Europe in under a century, and created a culture of expectation of growth that was essentially heretofore unseen. This culture and surplus population is what drives the age of colonization and age of exploration from the late 1400s to the late 1600s.