>>938705898 (OP)
I'd immediately scan the room for any threats. If Spider Man has been incapacitated, then Dr. Octopus or The Green Goblin are the likely culprits.
If I see one of them in the room, I would run back into the living room where I keep a home-defense shotgun. I would then come back into the room and dispatch the thread under the protection of the Castle Doctrine.
If no threat is detected after a thorough sweep, I would call the authorities to report the incident. I'd probably also fuck Spider Man in the butt just a little before taking off his binds.