Thread 510086063

Okay, unironically, what the fuck is this shit

>>510086063 (OP)
Very bad, very, very, very bad.

>>510086063 (OP)
Proteins going haywire aka the ultimate biological problem as there is no way to fix this shit

Google fatal insomnia, it's grim as fuck.

>>510086063 (OP)
The hair sides from a jew.

>>510086063 (OP)
Basically they replace normal enzymes motifs and start to biosynthesize abnormal biomolecules, then structural and functional features of proteins are defective, this provoking illness (mad cow disease)

>>510086063 (OP)
It's like cancer at the scale of proteins instead of cells.
Generally slowly destroys your brain in unusual ways before uniformly causing death. no cure.
Also, unlike cancer, prion diseases can spread between people

>>510086294
It's also incredibly difficult to destroy prions, meaning cleansing medical equipment after brain surgeries becomes a royal pain in the arse.

It's also basically, the reason anyone who's received a blood transfusion in the UK, since before 1982 (cant' remember exactly) aren't allowed to give blood.

>>510086438
>before
After rather. When the mad cow outbreak happened.

>>510086063 (OP)
>>510086294
Inbuilt clock to avoid humans living forever, even if we stop cell aging etc.

Prions take years/decades to show up with proper "infection", but theoretically a single prion will eventually replicate enough to kill you given enough time. Considering they need extreme heat (over 1000 degrees C) to be destroyed, last forever, and are smaller than a virus, they're probably everywhere and we all have at least a few.

Either our body can destroy/flush them somehow (as far as we know, it can't), or it's simply a matter of humans not living long enough for small amounts of prions to start causing issues within their lifespan. Live to 500 though and I bet prion diseases skyrocket.

>>510086168
And people think a Kind God exists.
No righteous God would ever create this.

>>510086063 (OP)
Good stuff. All meat eaters will die from this sooner or later. Good riddance you faggots.

>>510086063 (OP)
Fake

>>510086537
It’s a mutation in the prpc protein that is highly conserved in vertebrates and sillle prone to this misfolding that then misfiles others in a chain reaction. In a lab you can even infect fish. Interestingly carrion eaters like dogs have a mutated prp gene that is immune to misfolding and they don’t get prion disease.
Human activity like agriculture is probably the first time sensitive species like deer or sheep were ever in populations dense enough to spread it once it mutates. In the wild dogs would pick off of eat the animals with it before the proteins could build up.

>>510086063 (OP)
>what the fuck is this shit
It's an infective protein particle.
>can you kill it?
No, burning it is the only solution, but without proper incineration it will recrystalize and fly over everywhere.

Cooking destroys most pathogens. Cooking won't destroy a prion.

>>510086537
>Either our body can destroy/flush them somehow
Our bodies naturally produce small amounts od prions over time. Usually they're consumed by cellular autophagy, they only become a problem if a large amount of prions are aquired at once

>>510086257
Lol don't even need to go that far anon
https://www.sci.news/othersciences/chemistry/science-star-of-david-molecule-02176.html

>>510086063 (OP)
Protein function is normally mediated by shape. One of the levels of shapes are folding of a sheet of proteins. When these sheets misfold, things stop working because again, the shape determines function.
Diseased prions are so crazy because the misfoldes shape is in such a stable, low energy state that they can both arise spontaneously and induce nearby prions to misfold. Another consequence of this low energy state is that they maintain their structure for a very, very long time and are incredibly difficult to destroy.
That's pretty much the gist of it.

>>510086537
There are some drugs in development that can cure prion infections which are largely believed to be the cause of Alzheimer's disease.

>>510086063 (OP)
Professional schizophrenic here. ITS THE GOD PARTIXLE

>>510086063 (OP)
Like mad cow disease it's partially a genetic disease. Most people can deal with most forms of diseased prions just fine. However there is a small chance that you get infected with a prion your body is not capable of dealing with.

>>510086778
Good things the Bible says it was satan who tricked eve into eating the fruit. God told Adam and Eve not to eat it.

All of this could have been avoided if they just didn't eat it.

Stop blaming God for the things that satan did.

Why don't you spend some time criticizing satan instead of criticizing God?

>>510086063 (OP)
A biological nightmare. Satan's purest creation.

>>510086063 (OP)
Prions don't exist, it's just a theory someone came up with to explain mad cow disease. The likely cause was a slow acting virus.

>>510086778
Prions come from eating festering flesh, contaminated dirt and shit that your very biologic senses will tell you to not eat.
If you do not listen to your God given senses and eat that despicable stuff against your screaming souls' advice, then guess what faggot. You'll be punished.

Your lack of belief requires more faith.

>>510089193
God created everything, therefore that includes Satan, meaning it's god's fault, as is everything.

>>510090690
I wish you shitskins would fuck off.

>>510086063 (OP)
they think they will be godlike and that you are their science experiments
https://m.youtube.com/watch?v=tIFxVyzD_Kg

>>510086063 (OP)
one on the right is arranged like an antenna

>>510086294
Oncogenes

>>510086778
>Blaming God for evil
Enjoy hell anon, at least you won't be cold in winter.

one day we will conquer prisons so that our leaders and resume their cannibal lifestyle.

>>510086063 (OP)
The bible explains it. No wait the bible is just made up fairy tales by retards, doesn't explain shit about how the world really works, but people believed it back then due to retardation.

>>510086438
I heard that man was lifted recently but had no sauce.
Figured it was due to worrying about prions, after 85+% uptake of the clot shots turns retards into misfolded spike protein factories, was now a waste of time.

>>510092740
Sauce
https://www.aruplab.com/news/01-06-2023/individuals-who-lived-worked-parts-europe-now-eligible-donate-blood

>>510086063 (OP)
not political. wrong forum, faggot.

>>510093103
We'll make it political.

>>510086063 (OP)
Basically cancer that has absolutely no treatment options.

>>510086063 (OP)
It's literally just nature saying fuck you

>>510086063 (OP)
Vax status?

Has chronic wasting disease crossed over to humans? Is all venison suspect?

https://www.cbsnews.com/amp/news/hunters-die-prion-brain-disease-contaminated-deer-meat-report/

>>510091432
If you truly believe in a single God then you must accept God as the source of all good and evil. The alpha and omega. Creator of light and darkness. Good and evil. There is no one else. Isaiah 45:6-7

>>510094117
I know a guy who frequently traveled to Yellowstone to go down on whitetail deer whos pretty worried about that happening.

>>510089193
>>510091432
Hey dualists, did Satan invent evil or did it create itself ex nihilo?

>>510086063 (OP)
>Okay, unironically, what the fuck is this shit?
biological warfare.

>>510087326
Really? I thought most of the drugs in development were having fairly mediocre results thus far.

>DNA glitches out
>Your muscles are now bones
bruh

>>510086063 (OP)
Do prions survive nuclear hell fire?
That was a rhetorical question for you autists comprehension.

>>510095828
That's terrifying.
Taking splints to a horrible conclusion.

>>510086063 (OP)
Reminder:
>Brain titers exposed to nucleases reduced infectivity by >=99%.[39]

>>510086063 (OP)
V-status?

>>510086063 (OP)
The thermodynamic or metastable alternative folding configuration of proteins

>>510086294
The reason is that prions are often the "thermodynamic product" for protein configurations (and normally have an energy barrier vs the "productive" kinetic product that your body uses. So being exposed to the prion can essentially have the same effect as inserting a "seed crystal" in a solution.

>>510086935
Cooking to the "pyrolysis" point would, but in between that, heating would (depending on the given molecular structure) theoretically "improve" the kinetics and also increase volatility and likely make it more "spreadable"

>>510086063 (OP)
>what is it
Wrong way of thinking about it, OP.
:^)

>>510100552
That's the way I think of them.
Ice-9 but slower.

More than a little terrified, with all the ticks in seeing here now, that were never here before when they had 14000 since the ice melted to get here, the we'll all be allergic to meat soon.
Although maybe that's why the natives used to set the prairies on fire every couple of decades: not to create pasture for the Buffalo, but to clean the prairies of this most disgusting of pestilence.

>>510086063 (OP)
Spongebob

>>510100552
>So being exposed to the prion can essentially have the same effect as inserting a "seed crystal" in a solution.
So how does that work? Why does a healthy protein suddenly want to jump over that energy barrier and become a prion when it sees a prion?

>>510101430
If I had to guess the diseased prion gradually absorbs and disperses energy from the healthy prion. So the healthy prion gradually becomes diseased but the diseased prion never received enough energy to die/transform.
Just a guess though

>>510086063 (OP)
Not really /pol/. Try asking /sci/ but the tl;dr is Scary Shit that might be a side effect ofCow Cannibalism.

>>510089193
Ok sure. Let's see what the Satanic Commandments are...

>Do not give opinions or advice unless you are asked.
>Do not tell your troubles to others unless you are sure they want to hear them.
>When in another’s lair, show him respect or else do not go there.
>If a guest in your lair annoys you, treat him cruelly and without mercy.
>Do not make sexual advances unless you are given the mating signal.
>Do not take that which does not belong to you unless it is a burden to the other person and he cries out to be relieved.
>Acknowledge the power of magic if you have employed it successfully to obtain your desires. If you deny the power of magic after having called upon it with success, you will lose all you have obtained.
>Do not complain about anything to which you need not subject yourself.
>Do not harm little children.
>Do not kill non-human animals unless you are attacked or for your food.
>When walking in open territory, bother no one. If someone bothers you, ask him to stop. If he does not stop, destroy him.

They all seem quite tenable to me. All of your God's tricks are cruel, inhumane, and capricious. Your God is a bully with a magnifying glass on an ant hill. Satan just saw through his double standards and said: "fuck this shit, fuck you, fuck your whole system. I'm going to Earth, those guys are based."

>>510090784
The highest IQ holder: koreaman2224317, aka JongUn Kim.

Why do people believe this shit?

>>510098338
What do you mean by this?

>>510090784
Prions do not solely come from those things. In fact if you read up on the source you'd see that Fatal Familial Insomnia is genetic.
Meaning the only possible way to get it is to inherit it.

Meaning the only possible way to be cursed with this is for it to be God's will.

You christcucks are so fucking stupid. How can you claim to know of God when you are too afraid to tread in his domain? I tell you what, take 3 massive hits of DMT, go to the ethereal plane, meet your "God" and maybe you'll understand how little he actually told you about reality.

>>510101156
That's very insightful; I bet there is truth to that.

>>510102572
>bruhman listen, I know the secrets to the world dudebro
>listen man, I was on meth for 4 days straight and my homie Crustyhawk brought some dmt and acid bruh listen
>and it was all laid out to me, dudeman I just figured it out bruh
What was it?
>maaaan it just appeared dudepal! It was all there, man
What was it?
>nah mandude you just need to experience it bro I can't explain it but it's the truth man listen

This is who I'm debating with. I truly am in the wrong here.

>>510086294
>Unlike Cancer
Actually anon while there have been no proven cases of cancers spread between humans there are examples in nature of parasitic cancers among mammals in nature, such as the Tasmanian Devil face cancer.

Now obviously, this is a result of the species being incredibly violent and giving each other face wounds in their day-to-day lives allowing ruptured tumors to spread cancer cells from wound-to-wound contact. Still, it shows that parasitic cancers are completely possible.

>>510102430
Infected brain matter (which contained prions along with everything else in the brain) was treated with enzymes that specifically cut up nucleic acids (DNA and RNA) and NOT proteins. This reduced the infectivity of this brain matter, which implies that prions can't solely be responsible for the disease.

>>510094998
There was a recent study using fatal familial insomnia prp prions collected from mucus samples on a vole brain tissue culture substrate that showed their was infectious particles in human mucosa from who carried the genetic mutation and could be infectious. It wouldn’t take much for a prion to mutate and become infectious in humans like it is in deer. It’s evolved to be shed out of mucous cells in deer and last in the environment for a very long time.

>>510101430
Basic chemistry. Think of it like an organic chemistry experiment. Your reaction is going to trend in the direction of the stable lower energy state and will as long as it has enough energy to crest the activation energy needed for the reaction.


Infectious prions exist in a lower energy state than the functional protein and also lower the activation energy requirements of the healthy proteins they interact with converting healthy to the dysfunctional infectious version.

>>510103874
Alzheimer’s isn’t solely a prion disease. It impacts sleep spindles on an EEG completely differently. Sleep study is the gold standard to differentiate a prion diseased from regular dementias

>>510104490
I thought Alzheimer's was Aluminum poison or Diabetes type 3?

>>510103874
How do you know that this didn't damage an encoding sequence that would have made the brain matter more infectious? Prion diseases are highly linked to genetics, after all. It may be that the cause is the prion itself, but other proteins enable its spread.

>>510104606
I know less about it than prion diseases but I believe you are right, some thought is that it is tied to metabolic disease and plaques in the brain but a whole bunch of the researcher was tarnished with a major group committing fraud that led other researchers to make experiments off of results meant to scam grant givers

That drama didn’t interest me

lichen extract can slow down prions disease.
in fact its the only cure
jabtards it will not help due to altered kike genetics
i post this for the non coward jabbies only

>>510086063 (OP)
A bio weapon that even the kikes aren't immune from

>>510104768
Honestly you could be right, there are different versions of the prion gene in humans, some are pretty much immune and others are susceptible and people have more than one copy. If it was methylating the suspect copy or acting as a transcription factor for the resistant copy you would see the same result

>>510086063 (OP)
Just sting the prion with honeybee venom and watch it straighten out.
Problem solved.
Millennium prize when?

>>510090805
>the lack of God is God

Idiot

the limits of material world in our spacial dimensions caused this.

>>510102573
The only people that would know for sure are the chugs, and they've had any naturopathic insight beaten, bred and poisoned out of them with booze, drugs, and easy money.

Calling them 'stewards of the land' is just a sad joke at this point.

>>510086063 (OP)
I suspect that prl-8-53 can destroy prions.

>>510086063 (OP)
Prions are, unironicalky, fake and gay. A brief look into Kuru disease and the lead pedo researcher, Daniel Gajdusek, is enough to see through the jew psyop of nuke proof killer proteins. While Gajdusek, himself, didn't believe in Prions, the tests he conducted to prove his own theory of unconventional viruses, all if which failed miserably, apply equally to the existence of Prions

>>510086797
Is that why all the deer have wasting disease? From all the meat and brains they eat?

>>510090784
There's prions in the dirt. Prions in the plants. Prions in the groundwater. Prions in your local tapwater.

>>510106374
Same to you, sir. Same to you.

>>510086063 (OP)
They make other proteins they come into contact with into prions and that makes them fucking useless and kills you.

Basically the Muslims of proteins.

>>510086797
>Says meat eaters are bad
>Calls other people faggots

Oh boy

>>510086063 (OP)
Mother Nature's grand reset plan
It's only a matter of time before these little kill switches start infecting every single living being on earth.
>>510086778
Jesus fucking Christ, how braindead are you? A righteous God would absolutely 100 fucking percent wipe every last bit of life off this planet and start over again if he looked down and saw how fucked everything has become.

>>510108668
it honestly because cervids are especially prone to their protein misfolding combined with the fact deer have CNS tissue near their GI system meaning the proteins get transferred to waste much easier than other species

>>510108243
Yeah yeah, the earth is flat, christ is king, there was no moon landing; climate change isn't real; everyone is dying off from le vax. Nupol 2025 spastic <80 IQ.

>>510089193
If the animals didn't used to eat each other then why did God give them teeth?

Thinking the world is good by default and evil is some sort of internal sabotage is the reason leftism exists. Good things aren't good by default and have to we worked on actively to male them suck. Things suck by default and if something good happens it's cause someone explicitly violated the natural default through hard work to make shit better. Christianity's origin story asserts the opposite, which why the Christian world (and literally ONLY the Christian world) promotes fudgepacking

>>510086063 (OP)
Made up cartoon bullshit to get you to worship earth and Lucifer

>>510109214
>Only a matter of time
Where are you getting this information

>>510109249
Ok, great. Without any itregularity in thr smino acid sequence, newly translated linear proteins fold into "zombie" structures that, upon contact, turn other proteins into zombie form until the cell ruptures and the zombie proteins infect neighbouring cells.
Simple by folding irregularly, these otherwise normal proteins also become completely resistant to extreme heat, stomach acid, and enzymes. Once ingested, they are transported through the gut lining, pass easily across the blood brain barrier, then somehow remain I active for up to 20 years before zombifying the host proteins.

Besides all that, the history of kuru and life of Gajdusek should be enough to get you to at least question whether you've been lied to be the same type of people who claimed that the (((vax))) was 100% safe and effective

>>510086063 (OP)

you're not ready for this

https://en.wikipedia.org/wiki/Chirality

>>510086063 (OP)
Proteins that go bad. It wouldn't be a problem except they cause others to go bad growing exponentially and they can be transmitted in and out of the body.

>>510086063 (OP)
Prions are made-up nonsense created by Dr.Fauci's favorite Pedophile friend.
Here's a quick video on the "biologist" who made this "discovery."
https://rumble.com/v1j4pvf-the-kuru-guru.html?e9s=src_v1_sa%2Csrc_v1_ucp_a