Circumcision is evil
There are highly cost-effective interventions that could prevent one circumcision per dollar or more in expectation.
If we assume this reduces sexual pleasure by 20%( Most estimates seem to range between 10% and 90%, (Do note sexual sensation/pleasure is different than sexual satisfaction, effects on sexual satisfaction seem to be much smaller (although there is also very similar life satisfaction after couple years between new lottery winners and newly acquired paraplegics—cf. narrative life satisfaction vs. direct hedonic wellbeing) and it is notable that there is significant methodological difficulty in objectively measuring differences in pleasure, resulting in significant uncertainty here—although there is high information value in investigating further) and that sexual pleasure accounts for 5% of life happiness (I don’t think it’s unreasonable to think that a male with no sexual pleasure has lost at least 5% of his overall happiness on average; of course some males value much higher and some much lower) for average males we could get a rough Fermi estimate of 5% x 20% = 1% reduction in life satisfaction, and if we very, very crudely say that this is similar to losing 1% of 5O years of QALYs, this would be losing .5 QALYs per circumcision, and preventing one circumcision for one dollar would be 2$ per QALY.
I think malaria nets - Givewell’s perennial top charity ( https://www.givewell.org/international/technical/programs/insecticide-treated-nets ) - are estimated to be about $50 per QALY, so even estimates that were extremely more conservative, like if an intact foreskin only accounts for 5% of sexual pleasure (Despite being 1/3 to 1/2 the skin of the penis, being probably most of the nerve endings and almost all of the fine-touch nerve endings of the penis, in addition to providing several significant sexual functions important for both male pleasure and female comfort and vastly increased masturbatory pleasure)
If we assume this reduces sexual pleasure by 20%( Most estimates seem to range between 10% and 90%, (Do note sexual sensation/pleasure is different than sexual satisfaction, effects on sexual satisfaction seem to be much smaller (although there is also very similar life satisfaction after couple years between new lottery winners and newly acquired paraplegics—cf. narrative life satisfaction vs. direct hedonic wellbeing) and it is notable that there is significant methodological difficulty in objectively measuring differences in pleasure, resulting in significant uncertainty here—although there is high information value in investigating further) and that sexual pleasure accounts for 5% of life happiness (I don’t think it’s unreasonable to think that a male with no sexual pleasure has lost at least 5% of his overall happiness on average; of course some males value much higher and some much lower) for average males we could get a rough Fermi estimate of 5% x 20% = 1% reduction in life satisfaction, and if we very, very crudely say that this is similar to losing 1% of 5O years of QALYs, this would be losing .5 QALYs per circumcision, and preventing one circumcision for one dollar would be 2$ per QALY.
I think malaria nets - Givewell’s perennial top charity ( https://www.givewell.org/international/technical/programs/insecticide-treated-nets ) - are estimated to be about $50 per QALY, so even estimates that were extremely more conservative, like if an intact foreskin only accounts for 5% of sexual pleasure (Despite being 1/3 to 1/2 the skin of the penis, being probably most of the nerve endings and almost all of the fine-touch nerve endings of the penis, in addition to providing several significant sexual functions important for both male pleasure and female comfort and vastly increased masturbatory pleasure)