MDMA could be a safe and effective treatment for major depressive disorder (MDD), according to a new study, with participants showing “significantly reduced” depression symptoms eight weeks after receiving two doses of the drug a month apart.

No serious adverse effects were reported among the 12 subjects in the study, says the report, published last month in the British Journal of Psychiatry.

The new research looked at patients with a diagnosis of “single or recurrent episodes of MDD.” Subjects were excluded if they were pregnant or had psychotic disorders, mania, personality disorders, eating disorders with purging, substance use disorders or a host of other conditions.

Treatment involved two administrations of MDMA about four weeks apart, as well as follow-up phone calls and three 90-minute integration sessions. Dosage ranged from an 80-milligram dose at the first session to an offered 120-mg dose at the second session, with supplemental doses offered an hour to an hour and a half after the first dose.

Outcomes were measured through a standardized measure of depression symptoms, the Montgomery–Asberg Depression Rating Scale (MADRS), as well as the Sheehan Disability Scale (SDS), which measures functional impairment.

The study notes that scores of depression “were significantly reduced post treatment compared with baseline,” while functional impairment scores also “significantly decreased.”

“Consistent with previous studies of MDMA-AT for PTSD, we demonstrated both statistically and clinically significant reductions in the primary and secondary outcome measures of depression and functional impairment,” it says.

>https://www.marijuanamoment.net/mdma-significantly-reduced-major-depressive-disorder-symptoms-new-research-concludes/

>>512651389 (OP)
just walk it off

>>512651389 (OP)
After the serotonin dump you're pretty burned out. Mushrooms are better long term for depression

Oh it works great except for that black hole it creates in your seratonin processors . These kikes really want people to be psychologically mangled

>>512651389 (OP)
>No serious adverse effects were reported
MDMA abuse has well documented brain damage issues.
I've used to dozens of times but you need to take months in-between uses and really do the work on yourself to dig out of the hole.

Rolling for years without improvement will just leave you weak and worse off

>>512651389 (OP)
It’s pretty hard to be sad when you are rolling

It is incredibly useful for working through your issues; more useful than any therapist could be.

dumb thread, anyone who has done MDMA knows it turns you into a literal zombie afterwards, it burns a hole through your brain

>>512651448
>just walk it off
roof

You know what significantly reduces depression?
a clean living space
time outdoors
zero caffeine
but you can't monetize that so...

>>512652571
You can address the worst traumas and they wash away like rewriting your brain, but the serotonin dump is a major thing people shouldn't ignore.

>>512652644

Accurate

>>512652755

I am always amazed when I hear people who don't even smoke weed come up to me and be like "bro have you heard of MDMA"

I'm like "you can't be fucking serious", "have you actually tried that shit? there's a real reason MDMA is fucking illegal"

MDMA might honestly be the most psychoactive drug

I still remember the night(s) I took MDMA and this was years ago, that's how potent that shit is

>>512652692
i never took any mdma, wouldnt that serotinin dump being more easily fixable than whatever was causing the depression initially. also i think this probably will still only work with average or low iq people like standard therapies and other things they currently do

>>512652929

Bro you have 0 idea what you're talking about, there's a reason why guys who do it become retarded

It burns a hole through your brain, it'll be amazing, it'll hit harder than coke, you'll really feel the dancefloor and experience an orgasm on the dancefloor

But the next day you will be braindead

Any chemist niggers here able to explain to me why I don't get the serotonin dump comedown? I rolled quite frequently at high amounts (400-500mg crystal a rave) and it always lasts around 3 hours from the very first time I tried to every time after. No calmdown effects afterwards.
Feel fresh as hell the next day. Did I fry my brain some other way? I'm an adrenaline junky if that helps.

>>512653295

You fried your brain, register at a Tibetan monastery for walking and sitting medidations lessons

It's the only way to restore your brain cells, medidation, when done properly is able to make grey matter grow in the brain, it takes some training but I went to a monastery and they fixed me

>>512653438
How did I fry my brain if that's the case? It was the same after first use, and this is the only subtance I've ever used. Is it some other lifestyle factor?
Actually, maybe an improvement note, I think I understood what "joy" felt like when I used it, never experienced that feeling before.

Don't feel the need for any tibetian monks anon, my mood and mental capabilities are the same before and after (including in my intensive work).
Reason I'm asking is because I know the comedown exists as I see all my friends shit the bed with it the next day after a rolling.

>>512652692
I used to love going to raves and candy flipping. It was hella fun there is nothing better and more healing then rolling and banging hot rave sluts there is a serious need for this type of therapy

>>512653178
i literally said that i dont know what i am talking about. i never took the stuff, thats why i was asking questions.

>>512652564
>but you need to take months in-between uses
i wonder why this drug is so popular if you can't enjoy it very often. is the high so good that it's worth the wait?

>>512651483
Both MDMA and Shrooms have the opposite of the reported effect on others on myself. I get extremely self concious, paranoid and debilitatingly depressed each time I tried either one. Why is that? Does anyone know? Assuming my brain chemistry is vastly different than most.

>>512651389 (OP)
I love how science wants use to new all the drugs

>>512655748
That is incoherent, jeet. At least use a translator if you’re gonna try to larp as not a jeet with your meme flag retard.

>>512651389 (OP)
>could be a safe and effective treatmen
>safe and effective
So, not at all actually?

>>512651389 (OP)
Wow less resistance to scams

Disorder: men disagree with fake society and work instead of pay frauds like psychologists
Solution: drug them until they pay psychologists

>>512653295
You're dead and a demon is inhabiting where your soul once was. Your memory is just a naive mask that is unaware of the demon who is experiencing it.

>>512651389 (OP)
That's literally what it was developed and tested for in the 80s. This isn't new.

>>512655662
It's because you're more intelligent and your brain is more successful at "racing" the neural regrowth with new prunings to maintain your core ego.

Druggies would say you need a higher dose to "break through" and experience full ego death, but for what it's worth, when highly intelligent people have full breakthroughs they describe it as utter misery - shit like they feel like they got hit by a truck, attend their own funeral, then a demon tears their soul apart until they become stardust for 1 million eons until they rebuild and little and some memories return.
It also turns people into huge selfish assholes whose sense of God or goodness is replaced with the sole conviction that "I am the universe".

>>512652564
I’ve done MDMA, ketamine, mushrooms, and LSD many times across different settings and I think all these articles saying they cure mental illness is flat out bullshit.

>>512657064
The reason why people believe "I am the universe" is that full ego-death severs a person's connection to God. Everything you do from that point on in your life will either be neutral or count against your soul for hell. There's no more room for redemptive action.

>>512657108
What these (Soros funded) news headlines don't tell you is that while the majority of test cases report alleged success, everyone one of these trials has a few patients who go full mental breakdown and triple down on their trauma, especially the shrooms ones.

>>512657108
drugs can't cure mental illness because the only way to be sane is to have a very specific balance in neurotransmitters. drugs that influence the release or uptake in these neurotransmitters will only worsen the problem

>>512651389 (OP)
MDMA = ISRAEL EXPORT

look up shulgin. yikes

remember when mossad agents and interns were all over south florida directly preceding 9/11 and selling mdma to produce swells of untraceable cash as they were shadowing a few hijackers there

>>512657256
what do you mean megan fox and MGK did ayuhasca and realized everything is awesome bro

>>512657156
>"I am the universe"
That's not an ego death, that's an ego crisis
An ego death is "I surrender to the Universe"
Om Namo Narayanaya, innit.

>>512652644
Ironically, it seems to have similar effects to many psychiatric prescription drugs.

>>512657469
hindu demon worship, innit

>>512651389 (OP)
lel, lets make people roll, that will fix them. Lmao, I rolled all the time in my 20s. Even was a time rolling out like 3 times a week since I was a club kid addict. Ofc you feel good. But suicide sunday always around and theres nothing you can do to stop feeling like ass the next day except maybe 5htp and fruit smoothie. That was my go to after clubbing and warehouse parties.

>>512652564
>months
lmao ok noob. lemme guess you were only doing 1 point a night

>>512657064
>It also turns people into huge selfish assholes whose sense of God or goodness is replaced with the sole conviction that "I am the universe".

Mystical hippies who base their whole spirituality on their drug experiences.

>>512657469
You're dumb if you think "the universe is in my head" isn't you thinking you are the universe.

>>512651389 (OP)
Put sassafras back in root beer!

>>512655153
yes, it’s a hard drug and you will grind your teeth like a meth addict but you’ll feel incredible, especially if you are with other people and lights and music

>>512653178
I've done a lot of mdma and I would still bet money I could best you at an IQ test

>>512652564
> you need to take months in-between uses and really do the work on yourself

This is why so many people say “I’ve done psychedelics and they don’t help”. Doing the work is uncomfortable, people have to want to get better. Doing shrooms or MDMA and going clubbing with normies will only cause more anxiety. These studies that show benefits are under tightly controlled circumstances.

Months between trips also makes sense, not only for time to reflect but because it’s very easy to build tolerance with tryptamines.

>>512659553
this and the sex is incredible, basically you fall in love with every person you meet on molly, it boosts oxytocin, thats why they call it the love drug

>>512657064
This makes sense. I do have an uncomfortably high iq. Thank you.

>>512657064
LSD and other hallucinogens like 2C-I and stuff like that has a different effect on me where I start to feel an empathy I don’t normally have, and can understand things from others pov better (kike doctors say i have aspd).

>>512660522
Good thing is that my connection to God has never been severed. I resisted vehemently anything adjacent to ego death. A financial backer of sorts had me read this book (with an aptly named author) and I disagreed with everything in it and shit on it so much to them that the relationship was severed.

>>512651389 (OP)
That's odd because every time I take MDMA or Molly when I start to come down I get so depressed I think about killing myself.

>>512657064
>highly intelligent people have full breakthroughs they describe it as utter misery
In my experience the only people who are miserable in breakthrough dosages are extroverts. As they are entering a realm they pretend their whole life doesn't exist. But for the introvert it is a familiar land, and while you are getting a more intimate view of it, it is not entirely unfamiliar like for the extrovert.

>>512657064
>Druggies would say you need a higher dose to "break through" and experience full ego death,
>ego death
Youre referring to psychedelics, mate; not M
Also, either youre talking to the wrong people or you're making shit up. Taking *more* when you've had a bad trip is NOT the advice that should be given by experienced users.

>>512655662
In what environment did you take the M?

>/pol/ dipshits complimenting each other on their high IQ's
kek, it would take 5 of you to make a half-wit

>>512652644
I would always bounce back pretty quickly, maybe it works differently in non-faggots

>>512651389 (OP)
I mean it does the same thing as SSRI’s basically so this tracks

>>512656982
this is what I was thinking. must be a bunch of zoomers on here for it to have taken so long for someone to say this. if I remember correctly it was first used in marriage counciling .. and I doubt it would fry anyone's brain because I'm sure theyre only administering a small amount, not enough to make one roll balls.

I did the spravato nose spray and I definitely felt more miserable without it, but it was such a pain in the ass to get to, have to sit in a room in very close proximity to a total stranger for 2 hours.. scheduling was a nightmare.. it was horrible. I quit doing it. so many clinics are propping up to do it and they are garbage like this. not like the nice proper ones where you get your own room with the lights off and a music player and other things.

>>512657338
already know about that retard shulgin but the rest...

wha?.. I know so much about 9/11 I am shocked I don't know about this. you must elaborate.

>>512651389 (OP)
I find it fascinating how big pharma produces these papers to always come to the same conclusion: “those cheap to produce and popular drugs in the streets that most of you are hooked up to and eager to take, oh yeah they’re miracle drugs for all the problems that we’re going to get a huge markup on from the insurance and so on”.
Just saying…

>>512661423
Popular nightclub with friends
Concert with a girl and her sister
House party
Road trip in car with two buddies

All four times had a similar experience. Intense self consciousness (why is everybody looking at me) (I’m too thin) (Why is everybody else happy when i don’t feel happy). Intense paranoia (the cab driver is kidnapping me) (This guy talking to the girls sister wants to fight/kill me) (Somebody is going to rob me) (this nigger i have a problem with is going to show us at this party and stab me) and other assorted negative and depressive thoughts. Also, I am normally introverted amd very comfortable being alone or thinking about my life and doing self-reflection.

Do these kids look more happy or less happy than zoomers on pol

https://youtu.be/5yBvP3616Wc

>>512653178
>Bro you have 0 idea what you're talking about

lol zoom zoom who has zero fucking experience with the scene… you’re a lot like the zoomers who try to talk shit on cheeba

There is not one authentic word coming of ya’ll. Not one specific reference to names. No context, nothing…

The fact you think you can lecture to people who enjoyed the ‘90s Dutch DJ golden era is hilarious.

>>512661771
that's how uppers of any kind make me feel, and weed.

thats why I only like benzos and Opiates,, but benzos can make you act retard and not realize it if you take too many. Benzos and Opioids make my brain shut up.

>>512651389 (OP)
Oy vey just take more goy pills

Everyone who i know that has "major depression" is some kind of mentally and physically lazy retard that has to have all sorts of copes like 20 pets, stupid gimmicky shit like toys, videogames etc. smoking weed, shrooms, MDMA, DMT

Hey retard go outside in the sun light, eat healthy, work out, start thinking positively and put yourself so far out in the deep end of reality that you forget about your friends, family and world, aka going camping in the middle of fucking nowhere.

The entire reason these people are "depressed" is because they are obsessed with a issue and can't let it go, they are addicted to feeling sad, if you let your brain retardation win over your own will to live and survive you're too weak and retarded to survive this world anyway. Let it happen, darwin awaits you.

>>512652929
mdma was originally being used as a therapy drug before it took off into the party scene; so i'd argue that the serotonin dump could be easily manageable. but the thing to keep in mind is usage amount and tolerance levels

>>512661953
I only took benzo’s a handful of times but i remember that i would wake up the next day and feel like a million bucks. I sent brutally honest texts to people breaking down all the bullshit in their lives they were hiding from, burned some bridges but didn’t regret it. Tried to get a prescription after that but they refused thinking i was drug seeking.

>>512662165
benzos

>>512652644
Take an ssri and 5htp when you come down and you'll recover faster.

>>512662005
Based and camp pilled
(Foreign for God)

https://youtu.be/KHWGJS-RA6I

>>512662894
Not one person will click your jeet link saar

>>512662165
yeah. benzos give you balls of steel. even though I would do similar shit and likely really need to - i always felt embarrassed about it the next day lol

>>512663318
I care jeet sar

anyone know what i can take to get some actual energy and crush my fatigue

I need to help move a bunch of shit around but I have serious fatigue problems and even when I was on Adderall it just made me hyper focus on whatever I was doing when it kicked in.. so if thats looking on my phone then that is all im gonna do all day. caffeine makes me sleep. halp

>>512664030
Sleep for 10 hours you'll feel better

>>512664030
Caffeine makes me sleep too. Try noopept. Eat low carb, keto style.

>>512661771
That is fascinating, leaf.
I get those thoughts too, but with weed; so I can't touch that stuff. I love music and I love to dance, so this is what suppresses any paranoid thoughts to emerge; though that being said, the location needs to be pitch black at night and enclosed off from mainstream society.

> Also, I am normally introverted
Do you normally have a problem with social interactions, or suffer with social anxiety? Have you had a memorable prior life experience involving social distress/embarrassment/discomfort?

>>512651389 (OP)
garbage drug
trip for 1.5 hours, crash then feel braindead the whole next day
stims fry your mind your better off sticking with shrooms

>>512655662
You're not an NPC. See how they basically selected for NPCs in that study.

>>512651389 (OP)
Yeah and instead turns you into a psychothic mentally ill schizo

nice. lots of illegal drugs have legitimate uses. at the same time, its nobody's business if someone wants to ingest a molecule

>>512664030
how many decisions do you have to make during a day?
l-theanine and sleep, lots of sleep
caffeine adds more to the glutamate stress build-up so I wouldn't recommend it if you're fatigued

>>512664845
Not really. I am told i have “anti social traits” but i never had problems making friends or getting gfs and stuff. In my childhood i was mildly bullied, and always felt outcast but came out of that shell around 12-13 years old

>>512662005
Wise. I recommend that people check Iain McGilchrist, he puts into formal prose based on scientific research what this anon observed.

>>512651389 (OP)
So basically Jews made up a bunch of mental disorders that don't exist just so they could sell drugs that are usually illegal.

>>512651389 (OP)
lol until the subjects started coming down and wanted to kill themselves even more.

>>512653295
You have rocks in your head.

>>512665263
You have to go back jug meat

>>512662005
What has made you such a hateful wretch my son?

>>512651389 (OP)
it's was great stuff in the 90s but CAUSES clinical depression in users and I saw it ruin people

>>512651389 (OP)
>three 90-minute integration sessions
that's barely enough time for it to hit let alone come down off it

>>512661586
MDMA is a triple releaser.
SSRIs inhibit the release of serotonin from very specific serotonin receptors, allowing it to build up in the brain. It's the difference between Adderall and Ritalin, or Meth and Cocaine.

>>512651448
>just walk it off
/thread

>>512666113
it is all garbage for fools to make money for evil men

>>512651389 (OP)
Illicit drugs make the pain go away.

Yeah, no shit. Why did you think people take them?

Bull shit

>>512665975
Your skin is the color of poo sarr.

You know what causes deprtession, drugs, caffine, nicotine, booze, street and pharma drugs
stop taking this shit and goodbye anxiety and depression that are there for no reason, if you are depressed or anxious for a good reason like a death, disease, loss, or work or family stress, well that is life and drugs will only make it a hundred times worse

>>512661281
Maybe you should.

>>512666002
He has a very solid point but it's framed in the /pol/bant-hate way of instantly reacting. Which most of us just filter out to get to the meat of it, maybe the anon is not even meaning it that literally. It's shitty empty rhetoric is my point, many people use it here and many more exclusively use that that while never having a point so you're drowned into it, somehow it conditions you and let's be honest, it gets more (you)s, at least a guaranteed one from the person you insult.

>>512666779

>>512651389 (OP)
"Depression" doesn't exist; it is a psychosomatic illness that spreads through contact with psychiatric terminology.

MDMA just makes you into a luvved up horny retard, so of course it will make you feel anomalously good.

>>512666447
LMAO a talking mango lassi

>>512666886
It is like i said, not one person clicked your link jeet. Go see if you can dodge a train.

>>512655662
Interesting I get that with weed - hyper paranoid, self conscious, ultra anxiety to the point where I want to fuckin die. ecstasy though is a wonderful experience. shrooms been way too scared to try - bad trips are fucked dont even want to risk it due to my experience with weed.
the psychadelics thing is stupid. "ego death" "we're all one mannnn!!" - ok. now what? what do we do? tape eachother all together?

>>512662005
What the fuck is wronng with having a dog or playinng space invaders you arsehole? Nothing that's just your own pretension. Dogs are great and you know what games are too in all their forms. There's nothing great about freezing your arse of in a tent either.
>>512662005
>forget about your friends, family and world
So you run away because you can't deal with life. Right. You're right about not taking drugs but beyond that sound tarded

>>512666968
What link?

>>512666886
No one cares what you thinnk or wants you o this site.

>>512666884
>that spreads through contact with psychiatric terminology.
Just like "addiction", what ruins people people is learning about it and going to "therapy".

>>512651389 (OP)
>We are taking drug users at their word
One user reported that coke made him "the fucking king of the world woooo!"

>>512666968
I clicked the link just to spite you. It was some dumb SOAD music video so I closed it.

As somebody who's experienced in this topic. I must say it's not a great idea to legalize MDMA and honestly opoids are probably preferable to 95% of people who aren't still taking Adderall.

>>512666988
You pretending the other “sage” jeet in the thread talking shit to me isn’t the same jeet as you. Lmao. Ok poo

>>512667164
Crack users reported satisfaction with crack rocks and also reportedly enjoyed sucking dick recreationally.

>>512667021

>>512651389 (OP)
MIGA, on the other hand, serves Israel and rapes children.

>>512667243
Lmao you played yourself, faggot. Jeet lover, your mother will die in her sleep tonight.

>>512666455
Not everyone finds life satisfaction in growing potatoes, paddy.

>>512667097
Yup.
Continuous monetization of cultivated distress.
That's the game.

>>512667251
Oh I've been posting on many boards today, sorry. Don't recall a lot of stuff that happens on pleb boards

>>512665263
>>512665263
>I am told i have “anti social traits”
Are they mistaking "asocial" and "antisocial"?
anti-social is assigned to people originally referred to as psychopaths/sociopaths, ie. those who show no regard for others wellbeing and feel no empathy or remorse.
asocial are those who prefer solitude and don't bother (or struggle) with social interactions.

>>512667251
Reply to them once to let them know that no one cares what they think and they are not welcome or wanted on the site by anybody and move on. They are liars and frauds incapable of morality or truth, there is no point in interacting with them other that to tell them they are wasting their time posting because no one reads their posts of cares and they are not welcome here

>>512667338
In the morning i will wake up white, with a blessed life and you will wake up brown with a cursed life in the biggest shithole of the entire planet. I will actively spend part of my day making some of your countrymen’s day worse by my very existence as a superior specimen with a beautiful wife and those brown incels will seethe with rage. I will boycott bevery business employing a jeet. You will have no opportunity to do anything similar.

>>512667648
No, I have been to jail for arson for example and I have been charged with things like assault with a weapon and i could continue but you get the idea. When they say antisocial they mean it.

>>512667164
kek

>>512667839
You're a nigger, post your hand. Remember there's no shame in being a retard

>>512667807
You’re right. I have had a few glasses of red wine and got carried away.

>>512667902
OK tough guy, i believe you

>>512667320
Maybe you should, you degenerate junkie. Or just do us all a favor and neck yourself.

>>512651389 (OP)
>study about the drug effects that were already known in the 1970s and 80s when the drug first entered the fucking market

>>512653295
OMG SAME!!!

>>512651389 (OP)
During and long after my E using days (late 90s to mid 2000s) I was depressed and anxious as fuck. The depression was majorly caused by the E in my opinion. I haven't fully recovered as of 2025. I never had depression before first using ecstasy. It basically perma fryed my serotonin producing capabilities.

>>512667902
Ah fair. Well see now we are starting to piece the puzzle together.
I'm speculating that the prior life experiences in socially hostile environments and antisocial traits (relating to brain function) have a lot to do with this reverse effect of M.
M was designed for social openness; why it is triggering a reverse effect though is the baffling part, and unfortunately I only remember M's influence on the brain's serotonin receptors relating to wellbeing.
One could possibly pin this down to your environment if you're willing to do a test. Do you really enjoy music or dancing at all? Would the idea of vibing to music on M, somewhere alone in a personally safe location, seem outlandish?
Although keeping in mind you only mentioned the external threats that were perceived when on M, you never mentioned the other negative/depressive thoughts so that personal test may not be viable.

>>512668009
"Junkie" is a huge stretch but for a simple man like yourself any usage is deemed junkie.

Only time I took emma was at home alone with my gf and it gave me everytime a cuddle and Sex party for the entire night but weeks after my happiness receptors were blown out and gave me depressions.
Sure it can cure depressions as long as you take it but the coming down will be worse and worse if you come down.

>>512653295
It only ever made me furious but never got a comedown. I'm usually pretty chill.

>>512651389 (OP)
told you fuckers
https://www.youtube.com/watch?v=KcXeB1AvsTU

>>512651389 (OP)

It literally destroys neurotransmitter receptors in the brain

Maybe that works for people with severe depression the way Electro-convulsive shock therapy works: fry the brain until the depression is gone.

MDMA can only be done 1-2 times in your whole life without lasting brain damage.

Choose wisely.

>>512671346
>"Human neuroimaging studies have found reduced levels of the serotonin transporter in the brains of MDMA users, which is interpreted by some as evidence of neurotoxicity. However, other studies have not found consistent evidence of structural brain injury, and some experts argue that the observed changes may represent biochemical adaptations rather than permanent damage. A 2018 study analyzing data from neuroimaging studies and the Global Drug Survey suggested that the participants in these studies were heavy users, taking significantly more MDMA than the typical recreational user, which may skew the perception of long-term effects."

>>512652564
Therapeutic doses are usually much lower than recreational doses.
Meth is a good example since it is legally prescribed for narcolepsy and obesity.
No, people prescribed meth aren't meth heads, and they don't suffer the brain damage that junkies do.

>>512656931
Demons will give you good early morning fantasies involving their cocks. Dreams so vivid you taste their cum.

>>512661771
this is the type of person society produces hahahaha you’re literally living someone elses description of something, stupid cunt
>da taxi man gon kidnap me
>my arms are too skinny
>i wont do anything or accept it, just cry.
i hate faggots

>>512652683
>play parks
>rock climbing
>park entrance prices
>bottled water
>cleaner once a month
sounds like its been monetised.

>>512651389 (OP)
intermittent periods of depression are likely a necessary experience

>>512661842
i hate poland so much

>>512652564
>MDMA abuse

how you know they are are taking the same dose

>>512653807
You should have an MRI
Probably a psycho

>>512651389 (OP)
just take these new drugs to counter the side effect of those other drugs we gave you goy.

>MDMA fucls your head and leve should depressed
I always found people were taking far to much, I found halving the usualy dose would still give you a really good buzz and keep you going most of the night, with minimal side effects in the morning and countering the worst effects of a hangover.
It still made your dick shrink though, so even though I could get girls while I was on it I couldn't perform.

>>512651389 (OP)
>we can just reprogram people with chemicals

>>512651483
this. When I did molly I felt super down for a few days afterwards. On the other hand pretty much every time I do shrooms I feel extra good for like a week

so does semen retention. youll never feel depressed again but if you rarely do, it wont stick to you.
you dont need drugs to cure illnesses caused by jewish degeneracy

>>512666113
MDMA is basically Fen-Phen
>Fen-Phen pulled from markets because it causes Valvular Heart Disease
>Caused by 5-HT2 receptor agonism
>Turns out MDMA and all psychedelics, and SSRIs are also 5-HT2 receptor agonists
Unless the problem is actually the Fluorine "forever chemicals" then I'd stay away from all this if you don't want a heart attack at age 30.
>most SSRIs also have Fluorine
Time to buy water filters.

>>512673557
>I found halving the usualy dose would still give you a really good buzz
Because if you don't have it often, don't need much, and those effects can remain that way. It's when individuals are taking M constantly that their tolerance levels increase and they need more of it to get the same high as before, and then the downside effects can really kick in.

>>512674745
I was having it two or three times a month for a whole summer, which is how I figured out my perfect dosage. You only need to crank up the dose if you want the full body high. The way I had it felt like the buzz of having a few beers at the start of the night but at 3am instead. I wouldn't get shitfaced drunk, still have a pleasurable tingle, not have blown pupils or jaw clenching and still have the sociability without being obviously on drugs to everyone.
The next day I'd feel okay, more sleep deprived than anything. It was far superior to cochineal, that stuff made me miserable and just sobered me up, and friends were constantly scurrying about trying to find a place to snort a line

>>512675053
>cochineal
Cocaine fucking auto correct

I laugh when people still think MDMA is able to be made for street consumption. There is a reason why it hasn't since the 90s. On e of it's key ingredients is held in one high security location by the pharma who owns it. What you psy clowns are getting are MDMA analogues. Which is also why they show up on kits. Did MDMA burn back in the Dove days? Yes. If you overdo it like a faggot. So what you did was mostly do acid like a normal person. Es were for big benders.
> But I totally get REAL MDMa, trust me bro!
Fuck off. Don't reply to me.

https://www.youtube.com/watch?v=wm66ZFXjGY8

How about I don't want to get high at all
Being anything but sober or lightly buzzed off alcohol is deeply disturbing to me

>>512651389 (OP)
>marijuanamoment.net
kek

Ketamine treatment dosing every two weeks has way more realistic and quantifiable results than even mushrooms, which is also heavily documented at this point.
MDMA isn't even close to mushrooms let alone Ketamine treatment.
fuck off with your gay boy rave drugs.

>>512653295
It was probably amphetamine, king.
That or aspd.

>>512675053
I've got to consider your method then; because I've entertained the idea of going to a Latin (partner dancing) night while on M-- since (for those that don't know) one of the effects of M is heightened sensation to physical touch.

If you're against MDMA, you're boycotting Israel.

>>512651389 (OP)
>New Research Concludes
That is about as valid and trustworthy as an "expert opinion".
A new research finding that get covered by the media soon after they are published turn out be a fraud almost 100% of time.
The reason why research findings are published in academic journals is for other research insitutions to cross examine the findings and to allow other research institutions to carry out a study to test the same or a similar hypothesis.
It takes a long time for a new finding to be validated, and if it get an immediate exposure outside of the academic world, it is often because the vested interests are at work.
You this often with studies sponsored by pharmaceutical companies or the government.

>>512655153
It's called ecstacy for a reason

>>512651389 (OP)
Well you heard it here first, folks. The drug addict retards were right all along. You need an IQ of over 9000 to understand the genius of a homeless tweaker taking a watery diarrhea shit in a bus shelter.

>>512652353
Sounds like an overdosing issue, it's pretty safe if taken at normal doses

>>512652353
Scared of the void, pussy boi?

>>512675238
You probably have a huge ego and are a control freak desu. People take psychedelics to have an "ego death," your ego obviously wants to avoid that

>>512651483
>Mushrooms are better long term for depression
The only thing thats good for depression is a healthy diet and adequate resources for a stress free active lifestyle. Basically the only thing that should ever be recommended is a healthy lifestyle. Anything else is malpractice.

>>512677457
I've done psychedelics
I did weekly for a bit
I've learned the hard way that it's not good for you in the slightest
Even weed is poison for the soul

>>512655748
Fucking brown retard

>>512651389 (OP)
Retard medical science.
Fix the underlying problems in society (Niggers, spics, Jews, pakis, chinks) and taking drugs to deal with the hellscape wont be needed.
Pharma jews wrong that article.

>>512677457
MDMA is just entactogen which is an empathogen it doesn't have any psychedelic properties mud brown

>>512651483
>>512655662
>>512673804
They're talking about long term effects not the first few days afterwards, you drug addled morons.

All the druggies I see become LESS empathetic after such drugs. It might be that they only feel empathetic and "connected" in a self-aggrandising way. They act and talk like psychopaths after, which usually helps them to start doing stuff.

>>512678063
I don't make the rules

>>512678958
Your rules suck:
>"MDMA is sometimes classified as a psychedelic due to its ability to mildly alter visual perception and time perception, and because it can produce feelings of empathy and emotional openness. However, it is more commonly categorized as an entactogen, a class of drugs known for promoting feelings of connection and empathy, rather than as a classical psychedelic."
If you were to say to drug users that you take psychedelics, very few, if any, are going to think of M--they'll assume you mean mushrooms, acid, DMT, etc.

>>512653295
Increase doses by 10-20% and keep repeating, and record and dcoument the effects both during and 3 days post.


Our brains and digestive systems and chemical recetpives are all very similar but with tiny differences. Just be careful gooing to high

>>512679190
Sure. That aside though I have used it as the article described, to cure depression. It works partly because when you're actually depressed, you may not even realize it because it's just normal, but on MDMA you can look at your problems from a non-deprrseed state and then remember that different POV after it wears off. It also works against PTSD if you take it and meditate on the trauma because it's almost impossible to feel bad while on MDMA so you can look at the traumatic issue without it triggering negative flashbacks, which starts to rewire the brain to move past it.

>>512678958
I don't like drugs, but i know that only 5-HT2A receptor agonist are considered psychedelic afaik
MDMA releases massive amount of serotonin.
Psychedelics bind to serotonin receptors and mimic the release of serotonin without actually releasing serotonin
https://en.wikipedia.org/wiki/Vittorio_Erspamer?wprov=sfla1

>>512651389 (OP)
the study was too short to report the inevitable psychosis these sorts of drugs cause with prolonged use
it never ends well
stay sober and be a man

>>512676595
Yeah that should work out for you, you just need to figure out your amounts. My rule was half of what you would normally take then take a little bit more away. Always go with less than you think.

>>512651389 (OP)
>get high on drugs
>'I feel so happy'
Oh my science, thank you! Can I get some prescription whiskey please?

>>512657338
Shulgin played his fiddle or something at the Bohemian Grove faggot elitist party regularly. It's in his own book.

>>512679561
>one pretends to release serotonin
>the other releases a shit ton of serotonin

Same same but different, just like Pakistan, India, and Bangladesh.

Actually the come down more than the high was useful.
>Feel like absolute death
>Oh yeah, it isn't real, its just a dopamine thing
>Learn to recognize it as an impostor in future when occurring organically
>Get out of the depression doom loop
>Been largely fine ever since
Not a recommendation just personal experience.

>>512651389 (OP)
>drugs help depression
No shit, why do they think drugged up homeless zombies are using

>>512661281
Now you’re getting it

>drugs will fix a shit society

shalom!

>>512689638
It’s the same thought process behind “safe injection sites”
I bet some Karen is behind the study

>>512655662
>Both MDMA and Shrooms have the opposite of the reported effect on others on myself. I get extremely self concious, paranoid and debilitatingly depressed each time I tried either one. Why is that? Does anyone know? Assuming my brain chemistry is vastly different than most.
You dosed the MDMA too high or mixed it with stimulants like amphetamines or caffeine
~100mg is good for most people
It's possible to dose it too low as well. If you only take ~50mg, you get the stimulant effect without a sufficient serotonin dump to get feelings of well-being

New

study

just

dropped!

>>512653295
your low iq

>>512661771
Did you ever try taking ~100mg without mixing it with any other drugs?

>>512661771
>All four times had a similar experience. Intense self consciousness (why is everybody looking at me) (I’m too thin) (Why is everybody else happy when i don’t feel happy). Intense paranoia (the cab driver is kidnapping me) (This guy talking to the girls sister wants to fight/kill me) (Somebody is going to rob me) (this nigger i have a problem with is going to show us at this party and stab me) and other assorted negative and depressive thoughts. Also, I am normally introverted amd very comfortable being alone or thinking about my life and doing self-reflection.
this sounds like paranoia induced by consuming THC, caffeine, or amphetamines on top of the MDMA

>>512664030
>anyone know what i can take to get some actual energy and crush my fatigue
100 sessions of hyperbaric oxygen therapy per year if you're not a complete poorfag

You exit depression through hard work, not through chemicals

>>512690798
I dunno about that chief
Do you know how many drugs manual labourers do?

>>512690963
They do drugs bexause they are depressed, ans they are depressed because they are the bottom tier of thé social hierarchy

Manual work doesnt mean hard work, hard work means working lengthy hiurs

>demoralization thread encouraging drug use

>>512651389 (OP)
Lol the shit that fries your serotonin receptors?

>>512691464
Sure buddy, you keep believing that

>>512651389 (OP)
Im a psychologist and a huxley enjoyer so i also did a shitton of psychedelics and mdma and the like, mdma cannot be used long term and can do permanent damage to your natural seretonin resources if abused, its tolerance is relatively high altho not as high as psychedelics so overdoing it also doesnt work it just stops working while still damaging your brain. Mdma also has some sort of semi permanent tolerance in which overtime i always require more pills to get the same high even if years apart. Generally id advice against mdma as an antidepressant however the real solution would be to combine MDMA with EDMR and directly with synergy overwrite negative or traumatic memories in your hippocampus by using mdma to change the emotion-memory connection so you see the memory in a better light. We know both work for PTSD yet combining it has not been done as so far

>>512690798
No. You exit depression through genuine embodied connection with your community. When you rely on others and others rely on you, your life has meaning and purpose. “Hard work” is a meme. Hunter gatherers didn’t sit around thinking about doing “hard work”.

>>512692373
you are so full of shit

>>512691464
Lmao. So all we have to do to be happy is work “lengthy hours”? Wtf are you talking about, Frenchie? Tell that to all the suicidal and depressed Koreans working long hours.

>>512692582
Im not it could theoretically work

>>512692640
it's a reuptake inhibitor, it doesn't affect your production. You don't develop long term tolerance this is pure horse shit. I have used off an on over 30 years. It works great for ptsd and also depression, but effects only last around 4 months.

>>512651389 (OP)
>phone calls and three 90-minute integration sessions

Where these done the morning after or during the high?

>>512651389 (OP)
All the “treatments” for depression in the modern world are just bandaids trying cover up the deranged and disconnected way in which we live. Humans are meant to have embodied experiences with their community. We long to play a meaningful role for our society (not be a cog in a wheel or do some bullshit office job). Everything is transactional. And we are designing cities that are less walkable and beautiful. Life is taking place in a virtual world, in front of a screen, eating fake food, having fake and transactional interactions. Family structures are breaking down. Diversity is increasing and cultural cohesion is dying. Socializing takes place on a smart phone. Your role is now solely to help maximize shareholder profit. We don’t have strong bonds with our neighbors or families. The list goes on.

People were depressed at times and do it course get sick and have pain in the past. But the malaise we are experiencing today as a society is different. MDMA, shrooms, 5htp pills, HIIT, staring at the sun each morning, cold showers, etc… none of it is the answer.

Go outside. Meet people. Do things that matter and help others. That’s the solution. Of course the structure of society is making this harder. You are a “sucker” if you help others. You need to “get yours” and hustle. Etc. it’s a sickness. I don’t see how we come out of it.

>>512693103
> Based, so true
I grew up off grid and spent a lot of time in the wilderness, that's where I am happy, life has a different quality and meaning out there.

>>512651389 (OP)
it fuckin brain damages you thats why it "reduces depression"
when your brain is spiraling out of control of course there is less depression...
also it only reduces depression majorly while youre on it.

>>512693513
pharma shills out in force

All the posters posting negative things are working from the same script. Fuck you and your shitty prozac ssri crap, mda and mdma are the future.

>>512692940
>it's a reuptake inhibitor, it doesn't affect your production. You don't develop long term tolerance this is pure horse shit. I have used off an on over 30 years. It works great for ptsd and also depression, but effects only last around 4 months.
It first inhibits and then releases to get a massive triple monoamine dump. It's considered an SNDRA for a reason. It's basically enactogenic meth

>>512692940
If you dont abuse it its generally fine anon the problem is when its used too close to one another or in too high doses risking seretonin syndrome, stay safe

>>512692940
>it's a reuptake inhibitor
Thats a deceptive name. It actually still dumps all you serotonin in one go. L the reuptake part is what makes it seem to have a long lasting effect when in reality it's long out of your system by the time the effects start wearing off.

>>512690079
Not mixed with anything but alcohol and weed, and not every time. Regular standard dose everyone was doing, don’t know what

>>512690426
I don’t know the amount and yeah one of the times was by itself and one of the worst times

>>512651389 (OP)
>safe and effective
RIP to anyone who falls for this again

>>512695896
>we need more data
>so let’s just release it to the populace for trials

>>512651389 (OP)
Doesn't this directly imply that it causes brain damage? You might have to significantly alter the brain to cause changes this intense.

>>512651389 (OP)
Good luck getting the good stuff now though.
Most of the stuff I've seen the last 15 years has been cut with meth and other garbage.
Really kind of sad.

>>512652644
What, no one's ever heard of mass dosing b12 and b6 on your way down?
Fucking rookies.

>>512652683
Yeah, good luck realizing all that and improving your diet when the first and last thing that exists in your mind each day is killing yourself.
Depressed people need a quick temporary fix before they can even recognize the beginning and end of their problem starts with them and the way they're living.

>>512652871
Your brown and your iq is 90.
You 'remembering' mdma from years ago only tells us how pathetically boring your life is.
Live a little.
Or kys.