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"Shiksa" is a non-Jewish woman, often used to describe a non-Jewish woman romantically involved with a Jewish man.
The male version is "shegetz" (sometimes spelled "shagetz").
Root: From Hebrew (shiqes), meaning abomination, impure, or unclean thing. In biblical Hebrew, "shiqes" referred to something ritually impure or detestable, like certain non-kosher animals or idols.