>>715330880
The larger issue is that Edmund not only would not fix the game by placing new special rooms to help specific characters or synergies but actually would remove helpful synergies and Repentance only made the item pool much more polluted. Then introduced more characters that absolutely need the first couple of Devil Room items or Angel Items but could get easily hit making runs rely more and more on initial RNG.

As for enemies, the only enemy that sucks considerable dick is Delirium.