Search Results
6/17/2025, 10:43:43 PM
>>16700226
Not sure what you're exactly asking. Are you asking what would happen if a spermatogonium was transdifferentiated (perhaps using iPSC technology) into an oocyte then fertilized with a sperm from the same person?
Well I have the answer for a situation similar to this which does actually happen in nature often and it's called molar pregnancy.
How does this happen? sometimes females ovulate empty ova that contain no genetic material, and these ova sometimes get fertilized by two sperms (or one sperm that undergoes duplication), resulting in an ovum containing entirely male genetic material. The outcome of this? a molar pregnancy, specifically a complete hydatidiform mole.
Complete hydatidiform moles contain only placental tissue and no fetal tissue, they can also develop into cancer of the placenta known as choriocarcinoma.
Not sure what you're exactly asking. Are you asking what would happen if a spermatogonium was transdifferentiated (perhaps using iPSC technology) into an oocyte then fertilized with a sperm from the same person?
Well I have the answer for a situation similar to this which does actually happen in nature often and it's called molar pregnancy.
How does this happen? sometimes females ovulate empty ova that contain no genetic material, and these ova sometimes get fertilized by two sperms (or one sperm that undergoes duplication), resulting in an ovum containing entirely male genetic material. The outcome of this? a molar pregnancy, specifically a complete hydatidiform mole.
Complete hydatidiform moles contain only placental tissue and no fetal tissue, they can also develop into cancer of the placenta known as choriocarcinoma.
Page 1