>game character directly talks to you and acknowledges you're playing a game
>character turns directly to you to say an iconic line
>character knocks on the glass of your monitor
i love that kind of meta wackiness so much.

fish fillets (original, not NG) has a the two main characters constantly talking directly to the player. when i was little, one of the fish once said to not turn off the computer after i'm done playing, because it gets dark and she's scared.
i didn't turn off my computer for 3 days