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Anonymous /lgbt/40543331#40557455
7/31/2025, 8:51:31 AM
>>40557422
>>40557422
>What exactly is pio? Progesterone?
pioglitazone is a PPARy agonist that upregulates the creation of new small volume fat cells in feminine locations. it was made to treat diabetes patients, but eventually trannies realised its a great tool for feminising your fat distribution and some docs will even prescribe it to trannies now.

progesterone is a female hormone that boosts breast maturity, stem cell production, and fat cell lipid uptake in feminine areas. its essentially the third major hormone in female puberty after estrone, and estradiol. it should not be taken before the first year of HRT is complete, same with pio, as it may disturb the early effects of E2 and limit final results.

>How would that someone’s bone structure exactly.
prel is an afabs bone structure vs fat dist. as you can see actual bone structure isnt doing the heavy lifting here.