>>527010740
I've been having the most success with picrel
Carapace is necessary to kill crushers fast
Maniacs is optional, I prefer being able to kill mutants fast, and it helps against naked ragers. Your other options are either flak to also help with scab trash, or unyielding for bulwarks and bosses if you're running FotF.
Another anon recommended wrath recently, and I agree, it's the comfiest blessing to have. It still lets you horde clear very effectively without being powered up.
Second blessing is up to you. I like cranial grounding the most. I don't think blessings are that important, but wrath does make a difference.

The actual important part is running at least some damage in your skill tree. Duellist and sustained assault help a ton.