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7/19/2025, 11:53:03 AM
>A 3-year-old girl was referred to our pediatric outpatient clinic with breast development and vaginal discharge over a period of 6 months.
>The [gender affirming hormone therapy] of her transgender father was estradiol spray 6.12 mg applied to both forearms daily. After 6 months this was changed to estradiol gel 3.75 mg daily for 7 months. The gel was manually applied to the chest, abdomen, shoulders, and thighs.
>The father reported skin to skin contact on a daily basis. A physical examination of the girl revealed a Tanner stage III for breast and Tanner stage I for pubic hair development.
https://abstracts.eurospe.org/hrp/0097/hrp0097p2-91
>The [gender affirming hormone therapy] of her transgender father was estradiol spray 6.12 mg applied to both forearms daily. After 6 months this was changed to estradiol gel 3.75 mg daily for 7 months. The gel was manually applied to the chest, abdomen, shoulders, and thighs.
>The father reported skin to skin contact on a daily basis. A physical examination of the girl revealed a Tanner stage III for breast and Tanner stage I for pubic hair development.
https://abstracts.eurospe.org/hrp/0097/hrp0097p2-91
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