I'm thinking of using the Marvel Multiverse system for a lewd game, largely because powers can be used for fun kinks, and the players can't be killed while still suffering from failure and defeat. The vigor/Logic based 'hit point' pools means you can psychologically or physically brutalize the characters with differing results and situations, rather than having a singular pool of life force to work against.

Combining that with the wide variety of Pathfinder/Starfinder Races for fetish fuel looks like it could result in a particularly fun situation, especially if the settign is scifi prisoner/slave/captured specimen type stuff.