reached third layer with 90 happiness and without opiate usage, so far:
knee pouch with almost every kind of medication, some bandages and a splint. always on me, no fear of losing it after a bad fall.
medkit with all kinds of small usefull stuf - terrain scanner, ice pack, auxilliary medicine and a lot of food, mostly liquid (milk, soups, energy drinks, etc)
toolbox full of crafting materials of all kinds - ropes, foilage, glowfruits, alloys, circuits, scrap, powders
large backpack with everything else - water, food, some utilities and tools
pouch and a purse - buffers for items that later go into one of the better containers and crafting materials that i plan to sell
i think i am pretty decent at the game