Search Results
7/20/2025, 6:10:25 AM
>Photodynamic treatment increases the lifespan and oxidative stress resistance of Caenorhabditis elegans
>Highlights
>•A Photodynamic reaction with hypericin and orange light generates ROS in C. elegans.
>•Mild PDTr increases the lifespan and resistance to oxidative stress in C. elegans.
>•PDTr-induced oxidative stress resistance depends on NRF2, FOXO, AMPK, and p38 MAPK.
>•PDTr induces NRF2 and FOXO nuclear translocation and ctl-1, gst-4, and sod-3 expression.
>https://www.sciencedirect.com/science/article/pii/S0891584924004581
>Highlights
>•A Photodynamic reaction with hypericin and orange light generates ROS in C. elegans.
>•Mild PDTr increases the lifespan and resistance to oxidative stress in C. elegans.
>•PDTr-induced oxidative stress resistance depends on NRF2, FOXO, AMPK, and p38 MAPK.
>•PDTr induces NRF2 and FOXO nuclear translocation and ctl-1, gst-4, and sod-3 expression.
>https://www.sciencedirect.com/science/article/pii/S0891584924004581
Page 1