>>105985543
having 4 sticks of high capacity ram will gimp your max stable ram clocks to like 4000-4400mt/s and getting it to run at the advertised speed will be a nightmare

if you must have that much ram, look for a quad stick ram kit instead of mixing two dual stick kits, and find a board that specifically advertises 4 stick support in the QVL like msi's x870e tomahawk