I am in my home office right now completing some paperwork. Because my office has a lot of expensive electronics I keep a pistol in one of my drawers.
If that happened I would rush down with my 9mm Ruger. I have rabbits downstairs that I need to protect. In my state you can actually use lethal force to protect livestock. Rabbits are actually considered livestock in my state. Because they are house rabbits, castle doctrine also applies. Fear is assumed if they breach a locked door.