Mods this is /biz/ related, as every business dealing has an ethical dimension.
Darknet markets exist and deal in crypto, and the lion's share of wares are drugs. This board has plenty of discussion regarding all aspects of this field.

Now, it's relatively accessible and easy to grow drugs and sell online on DNMs if you have a grasp of e-commerce experience and a good handle on opsec, but is it actually a good thing to do, ethically speaking?
I used to vape nicotine for like 4-5 years, and I have had hemp/weed vapes/prerolls/dabs from time to time during that time, and I realized that it was harder and harder for me to use my brain effectively on them. Gradually I lost a decent amount of my cognitive ability and only recently started to get some of it back after a year of quitting cold turkey and enduring all the stress and withdrawal.
Is it ethical, in your opinion, to expose your customers to the same risks you may personally want to avoid? Should you care about your customers' wellbeing, or is this a pointless question?

As an aside, I miss the diy ethos of vape shops in the early 2010s where shit was fun and new and anyone could get involved and trade their products, as opposed to the Pakistani-Indian-Chinese monopoly that vaping and weed is today, which ends up fucking people up. I believe that if the old vibe came back, people would want to care about one another instead of fucking over the whole scene and by extension, the markets.
Just some of my thoughts, please share yours.