>>95965182
>Carter
The inspiration is pretty obvious. She toyed with incomprehensible forces, lost her humanity (just as planned) and can't turn back (not as planned). Same goes for the rest of the Miskatonic Circle, which in City's setting format would be more mad science based:
>H. West, a head in a jar brewing an army of zombies deep underground
>R. Blake, stared into the mirror world abyss until it stared back
>L. Whatley, who did a smash-or-pass with Lob Corps Abnormality line up, didn't pass once

Carter's Canto would probably focus on weird science, split between anomalies breaking the City's rhythm, and how the City reacts back (holy ultraviolence). So my initial thought is Carter having a full meltdown, Hieroglyph Clock taking over for good, and the abnormality flees underground after snatching a Bough from the company to do... something. The Sinners give chase, chased themselves by Claws now that the Circle's fuckery is no longer constrained to the Outskirts/Ruins. Race to the bottom before the City's finest cleanse the entire underground!

The final battle of the arc would be in an L-Corp research lab sinking into one of the Rivers as Carter/Hieroglyph Clock tries to blow open a hole into the Light again. If there's a twist, it's that Carter was aiding and abetting the whole time, wanting to give her mad project another shot, until somebody beats some sense back into her.

Or at least that's the best I can come up right now...
Note that I don't know shit about Limbus outside of wiki scrolling. If I got something way wrong, feel free to throw rocks.