I've been using W10 LTSC 2021 (2019 before it) for years but am now seriously considering switching to 11 LTSC due to an extremely esoteric OS+hardware problem that somehow I am the only one in the world to ever experience, even across multiple builds.
I have 100% narrowed it down to only occur on W10 21h1-22h2 and not W11, nor on W10 LTSC 2019.
Is there any reason not to? I actually like 11's UI more than 10 and it seemed pretty similar when I was testing it.