>any ending other than DON'T FEAR THE REAPER
nothing fits the theme of the setting or the story better; the goal is not for V to live, it isn't for him to destroy arasaka, it isn't for him to escape night city - you are told time and time again that his primary motivation is to become a Legend of Night City in the time he has left. This is why V's Reputation tracker talks constantly about rising through the ranks and achieving that status.
Yes; you can meet people and help them out along the way, and get wrapped up in all sorts-but your goal is to become a legend before you inevitably die.
even though it's suggested that the DFTR ending leads to Mr Blue Eyes helping cure V