>>96747318
If I remember correctly, the latest Amazon plot is that Garou and Pentex war against each other in the jungles. Hell, M20 even made that even the Technocracy is protecting it from further degradation.

Otherwise, perhaps you can expand the New Impergium (see image) to Amazon and the surrounding? It is certainly easier to implant new Impergium there than in Europe. You can even have Red Talon-Shadow Lords vs Silver Fangs intrigue and politics.