I really liked this thing when I first tried it while I was building my own "distro", I decided to use it as my "distro"'s package manager. It's from NetBSD and it advertises itself as this package manager that's kinda like portage because it fetches the source code of target package and builds and installs it to pre-defined prefix, such as /opt/pkg - which becomes kinda like a second root filesystem in the sense that it's the root for pkgsrc packages. Then I just added /opt/pkg/sbin and /opt/pkg/bin to the front of my path and it works as expected. It's all fine and dandy but for example the X11 packages seem partially broken at least on linux. It lacks some of the xf86-input/xf86-video driver packages and so on, overall desktop on linux is non-functional at least in VM (QEMU/KVM with vmware graphics driver, xf86-video-vmware and xf86-input-vmmouse), keyboard won't work and mouse doesn't work. I suspect this is because it's originally meant for NetBSD and NetBSD then somehow differs wildly from linux so some things are broken....
It would've been nice, but I guess it's not really good for desktop packages.