>>76515250
Primarily small molecule skill issues. They fall for "le fin" and "le min" that barely f'n work, then give up after some microneedling bullshit instead of finding shit like...
>mint water
>milk thistle
>mulberry root oil
>chuanxiong extract
>hemp oil
>sesame oil
>ephedra water extract
>angelica sinensis extract
>ginseng extract
>azelaic acid
>arginine
>vitamin B3
>vitamin B6
>vitamin D3
>vitamin E
>zinc sulfate
>NMN
>caffeine
>cetirizine
>latanoprost
>oryza sativa extract
>melatonin
>raspberry extract
>hyaluronic acid
>licorice water extract
>glycolic acid
>salvia miltiorrhiza water extract
>apple cider vinegar
>bromelain
>turmeric
>glycine max isoflavone extract
>DIM
>KX-826
>ketoconazole
>singlet oxygen
>chlorine dioxide solution
>hydrocortisone
>triamcinolone acetonide

>>76356397
So here's like 0.01% of the next-level trichology research out there..
>Curr Issues Mol Biol. 2025 Jan 20;47(1):68. doi: 10.3390/cimb47010068
>J. Xu, X. He, & R. Tian "Screening of Anti-Hair Loss Plant Raw Materials Based on Reverse Network Pharmacology and Experimental Validation"
>https://pmc.ncbi.nlm.nih.gov/articles/PMC11764182/
>we utilize reverse network pharmacology to screen for key targets of the Wnt/β-catenin signaling pathway and the TGFβ/BMP signaling pathway
>Licorice, salvia miltiorrhiza, mulberry leaf, ephedra and curcumae radix were found that may possess anti-hair loss effects.

>Cells 2025, 14(11), 779; doi: 10.3390/cells14110779
>A. Mehta, et al. "Revolutionary Approaches to Hair Regrowth: Follicle Neogenesis, Wnt/ß-Catenin Signaling, and Emerging Therapies"
>https://www.mdpi.com/2073-4409/14/11/779#
> The Wnt/B-catenin signaling pathway, a critical intracellular pathway responsible for hair follicle cycles, has gained traction as a target for therapeutic interventions. Studies show that stimulating this pathway leads to hair follicle growth, while its inhibition prompts hair follicle regression. Investigations demonstrate clinical efficacy of small molecule inhibitors and peptides, such as PTD-DBM, which activates the Wnt/β-catenin pathway by interfering with CXXC5, a negative regulator that inhibits pathway activation. Such therapies show potential as more effective treatment options than existing solutions such as finasteride and minoxidil.

>>76262720
u forgot the anon on here last summer who got terminal skin cancer with three failed surgeries after three consecutive days sunbathing? he got hella unlucky, but the sun is a real carcinogen in excess. use zinc oxide sunscreen and build up a tan with minimal late-day sun exposure. fuck the *benzones.

>>76264946
>it literally is the only solution
no it's literally mogged by stuff like topical mint water and milk thistle as 5-ARIs and the whole pathway is just kinda meh in hair grow; you gotta go super deep in all the weird growth factors minoxidil ain't hitting to really get lots of hair.
>t. thinks the FDA a bunch of retarded fossils that ain't understand research chemicals