If Makima was Judah and Nayuta is Sister Luna (Judah) then Nayuta has to "perish" (whether in body or in mind) in order to bring about her Tree Luna Judah equivalent. It is known.

>>281121147
He'll get a hallucination of Makima saying 'save me chainsaw man' and kill both Asa and Yoru. Nostradamus told me so.